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Diagnosing Psoriatic Arthritis from the Dermatologist's View.

Cho HH, Kim BS - J Lifestyle Med (2013)

Bottom Line: Psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis.It is considered a unique arthropathy with distinct clinical and radiologic features.Biologic agents, including TNF-α inhibitors and anti-IL12/23 agents, have shown dramatic improvement.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, School of Medicine, Pusan National University Hospital, Busan ; Pusan National University Yangsan Hospital, Yangsan, Korea.

ABSTRACT
Psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis. It is considered a unique arthropathy with distinct clinical and radiologic features. Up to 40% of patients with psoriasis may develop psoriatic arthritis. Psoriasis usually precedes psoriatic arthritis, so dermatologists are in a critical position for screening patients of psoriatic arthritis early in the disease course. Psoriatic arthritis may be challenging to diagnose, especially for dermatologists, because it has an insidious disease course, non-specific symptoms, and no specific biomarkers. Psoriatic arthritis is a polygenic autoimmune disorder of unknown etiology, but immunologic roles have recently been validated. In recent years, treatment modalities have rapidly advanced in the fields of psoriasis and psoriatic arthritis. Biologic agents, including TNF-α inhibitors and anti-IL12/23 agents, have shown dramatic improvement.

No MeSH data available.


Related in: MedlinePlus

Dactylitis of right index finger.
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Related In: Results  -  Collection

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f1-jlm-03-85: Dactylitis of right index finger.

Mentions: Dactylitis is defined as diffuse swelling of a digit, or ‘sausage-shaped digit’ (Fig. 1). It may occur in one or more digits concomitantly with the typical signs of inflammation, such as swelling, redness, pain, warmth, and limited range of motion. Dactylitis has long been recognized as one of the cardinal features of PsA [1]. It is an expression of active PsA and will respond well to anti-TNF-α therapy [24]. Table 2 compares PsA with other rheumatologic conditions.


Diagnosing Psoriatic Arthritis from the Dermatologist's View.

Cho HH, Kim BS - J Lifestyle Med (2013)

Dactylitis of right index finger.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4390746&req=5

f1-jlm-03-85: Dactylitis of right index finger.
Mentions: Dactylitis is defined as diffuse swelling of a digit, or ‘sausage-shaped digit’ (Fig. 1). It may occur in one or more digits concomitantly with the typical signs of inflammation, such as swelling, redness, pain, warmth, and limited range of motion. Dactylitis has long been recognized as one of the cardinal features of PsA [1]. It is an expression of active PsA and will respond well to anti-TNF-α therapy [24]. Table 2 compares PsA with other rheumatologic conditions.

Bottom Line: Psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis.It is considered a unique arthropathy with distinct clinical and radiologic features.Biologic agents, including TNF-α inhibitors and anti-IL12/23 agents, have shown dramatic improvement.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, School of Medicine, Pusan National University Hospital, Busan ; Pusan National University Yangsan Hospital, Yangsan, Korea.

ABSTRACT
Psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis. It is considered a unique arthropathy with distinct clinical and radiologic features. Up to 40% of patients with psoriasis may develop psoriatic arthritis. Psoriasis usually precedes psoriatic arthritis, so dermatologists are in a critical position for screening patients of psoriatic arthritis early in the disease course. Psoriatic arthritis may be challenging to diagnose, especially for dermatologists, because it has an insidious disease course, non-specific symptoms, and no specific biomarkers. Psoriatic arthritis is a polygenic autoimmune disorder of unknown etiology, but immunologic roles have recently been validated. In recent years, treatment modalities have rapidly advanced in the fields of psoriasis and psoriatic arthritis. Biologic agents, including TNF-α inhibitors and anti-IL12/23 agents, have shown dramatic improvement.

No MeSH data available.


Related in: MedlinePlus