Limits...
Risk factors for subdural haematoma in patients with spontaneous intracranial hypotension.

Xia P, Hu XY, Wang J, Hu BB, Xu QL, Zhou ZJ, Lou M - PLoS ONE (2015)

Bottom Line: The clinical and radiographic characteristics of these 93 patients were analyzed, and then univariate analysis and further multiple logistic regression analysis were performed to identify the potential risk factors for the development of SDHs.However, multivariate analysis only included the latter three factors.Our study reveals important radiological manifestations for predicting the development of SDHs in patients with SIH.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou, 310016, China; Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, 3 East Qingchun Road, Hangzhou, 310016, China.

ABSTRACT
Subdural haematoma (SDH) is a potentially life-threatening complication in patients with spontaneous intracranial hypotension (SIH). In serious cases, SIH patients who present with SDHs develop neurological deficits, a decreased level of consciousness, or cerebral herniation, and may even require an urgent neurosurgical drainage. Despite numerous publications on SDHs, few report its potential risk factors in patients with SIH. In this study, we retrospectively investigated 93 consecutive SIH patients and divided them into an SDH group (n = 25) and a non-SDH (NSDH) group (n = 68). The clinical and radiographic characteristics of these 93 patients were analyzed, and then univariate analysis and further multiple logistic regression analysis were performed to identify the potential risk factors for the development of SDHs. The univariate analysis showed that advanced age, male gender, longer clinical course, dural enhancement, and the venous distension sign were associated with the development of SDHs. However, multivariate analysis only included the latter three factors. Our study reveals important radiological manifestations for predicting the development of SDHs in patients with SIH.

No MeSH data available.


Related in: MedlinePlus

Typical MRI manifestation of the venous distension sign.T1-weighted MRI through the midportion of the dominant transverse sinus shows the venous distension sign (box).
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4390346&req=5

pone.0123616.g002: Typical MRI manifestation of the venous distension sign.T1-weighted MRI through the midportion of the dominant transverse sinus shows the venous distension sign (box).

Mentions: The brain MRI was performed using a 1.5-T System (Siemens, Germany) with a head-sense-coil. Midsagittal T1-weighted MRIs were selected for the evaluation of brain sagging, which was defined as either cerebral aqueduct displacement ≥1.8 mm or cerebellar tonsil displacement ≥4.3 mm (Fig 1) [25]. The midportion of the dominant transverse sinus on sagittal T1-weighted MRIs was used for assessing the venous distension sign (VDS), as proposed by Farb et al. (Fig 2) [26]. Dural enhancement was evaluated on axial and coronal T1-weighted images with gadolinium enhancement (Fig 3).


Risk factors for subdural haematoma in patients with spontaneous intracranial hypotension.

Xia P, Hu XY, Wang J, Hu BB, Xu QL, Zhou ZJ, Lou M - PLoS ONE (2015)

Typical MRI manifestation of the venous distension sign.T1-weighted MRI through the midportion of the dominant transverse sinus shows the venous distension sign (box).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4390346&req=5

pone.0123616.g002: Typical MRI manifestation of the venous distension sign.T1-weighted MRI through the midportion of the dominant transverse sinus shows the venous distension sign (box).
Mentions: The brain MRI was performed using a 1.5-T System (Siemens, Germany) with a head-sense-coil. Midsagittal T1-weighted MRIs were selected for the evaluation of brain sagging, which was defined as either cerebral aqueduct displacement ≥1.8 mm or cerebellar tonsil displacement ≥4.3 mm (Fig 1) [25]. The midportion of the dominant transverse sinus on sagittal T1-weighted MRIs was used for assessing the venous distension sign (VDS), as proposed by Farb et al. (Fig 2) [26]. Dural enhancement was evaluated on axial and coronal T1-weighted images with gadolinium enhancement (Fig 3).

Bottom Line: The clinical and radiographic characteristics of these 93 patients were analyzed, and then univariate analysis and further multiple logistic regression analysis were performed to identify the potential risk factors for the development of SDHs.However, multivariate analysis only included the latter three factors.Our study reveals important radiological manifestations for predicting the development of SDHs in patients with SIH.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou, 310016, China; Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, 3 East Qingchun Road, Hangzhou, 310016, China.

ABSTRACT
Subdural haematoma (SDH) is a potentially life-threatening complication in patients with spontaneous intracranial hypotension (SIH). In serious cases, SIH patients who present with SDHs develop neurological deficits, a decreased level of consciousness, or cerebral herniation, and may even require an urgent neurosurgical drainage. Despite numerous publications on SDHs, few report its potential risk factors in patients with SIH. In this study, we retrospectively investigated 93 consecutive SIH patients and divided them into an SDH group (n = 25) and a non-SDH (NSDH) group (n = 68). The clinical and radiographic characteristics of these 93 patients were analyzed, and then univariate analysis and further multiple logistic regression analysis were performed to identify the potential risk factors for the development of SDHs. The univariate analysis showed that advanced age, male gender, longer clinical course, dural enhancement, and the venous distension sign were associated with the development of SDHs. However, multivariate analysis only included the latter three factors. Our study reveals important radiological manifestations for predicting the development of SDHs in patients with SIH.

No MeSH data available.


Related in: MedlinePlus