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A 3-month, randomized, double-blind, placebo-controlled study evaluating the ability of an extra-strength marine protein supplement to promote hair growth and decrease shedding in women with self-perceived thinning hair.

Ablon G - Dermatol Res Pract (2015)

Bottom Line: MPS-treated subjects achieved a significant increase in the number of terminal hairs within the target area (P < 0.0001) which was significantly greater than placebo (P < 0.0001).MPS use also resulted in significantly less hair shedding (P = 0.002) and higher total Self-Assessment (P = 0.006) and Quality of Life Questionnaires scores (P = 0.035).There were no reported adverse events.

View Article: PubMed Central - PubMed

Affiliation: Ablon Skin Institute Research Center, Manhattan Beach, CA 90266, USA.

ABSTRACT
An oral marine protein supplement (MPS) is designed to promote hair growth in women with temporary thinning hair (Viviscal Extra Strength; Lifes2good, Inc., Chicago, IL). This double-blind, placebo-controlled study assessed the ability of MPS to promote terminal hair growth in adult women with self-perceived thinning hair associated with poor diet, stress, hormonal influences, or abnormal menstrual cycles. Adult women with thinning hair were randomized to receive MPS (N = 30) or placebo (N = 30) twice daily for 90 days. Digital images were obtained from a 4 cm(2) area scalp target area. Each subject's hair was washed and shed hairs were collected and counted. After 90 days, these measures were repeated and subjects completed Quality of Life and Self-Assessment Questionnaires. MPS-treated subjects achieved a significant increase in the number of terminal hairs within the target area (P < 0.0001) which was significantly greater than placebo (P < 0.0001). MPS use also resulted in significantly less hair shedding (P = 0.002) and higher total Self-Assessment (P = 0.006) and Quality of Life Questionnaires scores (P = 0.035). There were no reported adverse events. MPS promotes hair growth and decreases hair loss in women suffering from temporary thinning hair. This trial is registered with ClinicalTrials.gov Identifier: NCT02297360.

No MeSH data available.


Related in: MedlinePlus

Subject 42. The number of terminal and vellus hairs at baseline (left) increased significantly after 90 days of treatment (right). The 4 cm2 target area of the scalp is shown in the middle and bottom rows.
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fig1: Subject 42. The number of terminal and vellus hairs at baseline (left) increased significantly after 90 days of treatment (right). The 4 cm2 target area of the scalp is shown in the middle and bottom rows.

Mentions: Among the MPS-treated subjects, there was a significant increase in the mean number of terminal hairs from 178.3 (7.8) at baseline to 235.8 (18.4) at Visit 2 (f(1,29) = 362.0, P < 0.0001) but not among placebotreated subjects from 178.2 (9.6) to 180.9 (18.8) (f(1,29) = 1.25, P = 0.273) (Table 1). Consequently, the number of terminal hairs among MPS-treated subjects was also significantly greater than placebo-treated subjects at Visit 2 (f(1,58) = 200.4, P < 0.0001) due to the greater increase among the MPS-treated subjects (MPS: D0:178.3 ± 8; D90:235.8 ± 18; placebo: D0:178.2 ± 10, D90:180.9 ± 18). Changes in the clinical appearance of two treated subjects at baseline and after 90 days of treatment are apparent in Figures 1 and 2.


A 3-month, randomized, double-blind, placebo-controlled study evaluating the ability of an extra-strength marine protein supplement to promote hair growth and decrease shedding in women with self-perceived thinning hair.

Ablon G - Dermatol Res Pract (2015)

Subject 42. The number of terminal and vellus hairs at baseline (left) increased significantly after 90 days of treatment (right). The 4 cm2 target area of the scalp is shown in the middle and bottom rows.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4389977&req=5

fig1: Subject 42. The number of terminal and vellus hairs at baseline (left) increased significantly after 90 days of treatment (right). The 4 cm2 target area of the scalp is shown in the middle and bottom rows.
Mentions: Among the MPS-treated subjects, there was a significant increase in the mean number of terminal hairs from 178.3 (7.8) at baseline to 235.8 (18.4) at Visit 2 (f(1,29) = 362.0, P < 0.0001) but not among placebotreated subjects from 178.2 (9.6) to 180.9 (18.8) (f(1,29) = 1.25, P = 0.273) (Table 1). Consequently, the number of terminal hairs among MPS-treated subjects was also significantly greater than placebo-treated subjects at Visit 2 (f(1,58) = 200.4, P < 0.0001) due to the greater increase among the MPS-treated subjects (MPS: D0:178.3 ± 8; D90:235.8 ± 18; placebo: D0:178.2 ± 10, D90:180.9 ± 18). Changes in the clinical appearance of two treated subjects at baseline and after 90 days of treatment are apparent in Figures 1 and 2.

Bottom Line: MPS-treated subjects achieved a significant increase in the number of terminal hairs within the target area (P < 0.0001) which was significantly greater than placebo (P < 0.0001).MPS use also resulted in significantly less hair shedding (P = 0.002) and higher total Self-Assessment (P = 0.006) and Quality of Life Questionnaires scores (P = 0.035).There were no reported adverse events.

View Article: PubMed Central - PubMed

Affiliation: Ablon Skin Institute Research Center, Manhattan Beach, CA 90266, USA.

ABSTRACT
An oral marine protein supplement (MPS) is designed to promote hair growth in women with temporary thinning hair (Viviscal Extra Strength; Lifes2good, Inc., Chicago, IL). This double-blind, placebo-controlled study assessed the ability of MPS to promote terminal hair growth in adult women with self-perceived thinning hair associated with poor diet, stress, hormonal influences, or abnormal menstrual cycles. Adult women with thinning hair were randomized to receive MPS (N = 30) or placebo (N = 30) twice daily for 90 days. Digital images were obtained from a 4 cm(2) area scalp target area. Each subject's hair was washed and shed hairs were collected and counted. After 90 days, these measures were repeated and subjects completed Quality of Life and Self-Assessment Questionnaires. MPS-treated subjects achieved a significant increase in the number of terminal hairs within the target area (P < 0.0001) which was significantly greater than placebo (P < 0.0001). MPS use also resulted in significantly less hair shedding (P = 0.002) and higher total Self-Assessment (P = 0.006) and Quality of Life Questionnaires scores (P = 0.035). There were no reported adverse events. MPS promotes hair growth and decreases hair loss in women suffering from temporary thinning hair. This trial is registered with ClinicalTrials.gov Identifier: NCT02297360.

No MeSH data available.


Related in: MedlinePlus