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A case of radiotherapy for an advanced bronchial carcinoma patient with implanted cardiac rhythm machines as well as heart assist device.

Scobioala S, Ernst I, Moustakis C, Haverkamp U, Martens S, Eich HT - Radiat Oncol (2015)

Bottom Line: Despite partial localization of the active ICD in the radiation field, the tumor was treated without inappropriate shock delivery during radiation treatment and over twelve months afterwards.The reduced tumor size as well as tumor metabolic activity were observed by PET-CT three months after radiation treatment.The reduced dyspnea and cough over the first four months after treatment were observed.In conclusion, tumor shrinkage and temporary clinical improvement of the patient as well as no technical complications of implanted cardiac devices were achieved by the radiation treatment.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiotherapy and Radiooncology, University Hospital of Muenster, Muenster, 48149, Germany. Sergiu.Scobioala@ukmuenster.de.

ABSTRACT
We present a case of radiotherapy for a 66-year-old patient with squamous cell carcinoma on the left main bronchus undergoing implantation of pacemaker, implantable cardioverter defibrillator (ICD) as well as cardiopulmonary support (CPS) device. The radiation area was determined according to 4D List Mode positron emission tomography-computed tomography (PET-CT) data. Planning Target Volume (PTV) included a part of the active ICD. For the optimal tumor coverage and sparing of both the implantable cardiac devices and organs at risk, we combined the conformal radiotherapy with stereotactic body radiotherapy (SBRT) using helical tomotherapy. The prescription dose of 25.2Gy was applied by conventional radiotherapy. SBRT was performed hypofractionated with a prescription dose of 35Gy in 5 fractions. A dynamic electrocardiogram was performed during every radiation fraction. The implanted aggregates were checked three times a week. Despite partial localization of the active ICD in the radiation field, the tumor was treated without inappropriate shock delivery during radiation treatment and over twelve months afterwards. The reduced tumor size as well as tumor metabolic activity were observed by PET-CT three months after radiation treatment. The patient exhibited no signs of pneumonitis on the last radiological follow-up examination six months after radiotherapy. The reduced dyspnea and cough over the first four months after treatment were observed.In conclusion, tumor shrinkage and temporary clinical improvement of the patient as well as no technical complications of implanted cardiac devices were achieved by the radiation treatment.

No MeSH data available.


Related in: MedlinePlus

PTV in relation to implanted cardiac devices: a) breathing- and heart beat-guided definition of PTV on the basis of 4D List Mode PET/CT; b) partial localization of the ICD in the radiation field. 1- cardiac pacemaker, 2 – ICD, 3 – CPS device.
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Fig2: PTV in relation to implanted cardiac devices: a) breathing- and heart beat-guided definition of PTV on the basis of 4D List Mode PET/CT; b) partial localization of the ICD in the radiation field. 1- cardiac pacemaker, 2 – ICD, 3 – CPS device.

Mentions: Target movement caused by breathing and heart beat was detected by 4D List Mode PET/CT (Figure 2). During this procedure the special integrated detector - Anzai Gating system on the Siemens camera - registered the motion amplitude of the indicated target during at least ten minutes. Each 4D PET scan was reconstructed into an ungated static image and analyzed by software [18,19].Figure 2


A case of radiotherapy for an advanced bronchial carcinoma patient with implanted cardiac rhythm machines as well as heart assist device.

Scobioala S, Ernst I, Moustakis C, Haverkamp U, Martens S, Eich HT - Radiat Oncol (2015)

PTV in relation to implanted cardiac devices: a) breathing- and heart beat-guided definition of PTV on the basis of 4D List Mode PET/CT; b) partial localization of the ICD in the radiation field. 1- cardiac pacemaker, 2 – ICD, 3 – CPS device.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4389884&req=5

Fig2: PTV in relation to implanted cardiac devices: a) breathing- and heart beat-guided definition of PTV on the basis of 4D List Mode PET/CT; b) partial localization of the ICD in the radiation field. 1- cardiac pacemaker, 2 – ICD, 3 – CPS device.
Mentions: Target movement caused by breathing and heart beat was detected by 4D List Mode PET/CT (Figure 2). During this procedure the special integrated detector - Anzai Gating system on the Siemens camera - registered the motion amplitude of the indicated target during at least ten minutes. Each 4D PET scan was reconstructed into an ungated static image and analyzed by software [18,19].Figure 2

Bottom Line: Despite partial localization of the active ICD in the radiation field, the tumor was treated without inappropriate shock delivery during radiation treatment and over twelve months afterwards.The reduced tumor size as well as tumor metabolic activity were observed by PET-CT three months after radiation treatment.The reduced dyspnea and cough over the first four months after treatment were observed.In conclusion, tumor shrinkage and temporary clinical improvement of the patient as well as no technical complications of implanted cardiac devices were achieved by the radiation treatment.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiotherapy and Radiooncology, University Hospital of Muenster, Muenster, 48149, Germany. Sergiu.Scobioala@ukmuenster.de.

ABSTRACT
We present a case of radiotherapy for a 66-year-old patient with squamous cell carcinoma on the left main bronchus undergoing implantation of pacemaker, implantable cardioverter defibrillator (ICD) as well as cardiopulmonary support (CPS) device. The radiation area was determined according to 4D List Mode positron emission tomography-computed tomography (PET-CT) data. Planning Target Volume (PTV) included a part of the active ICD. For the optimal tumor coverage and sparing of both the implantable cardiac devices and organs at risk, we combined the conformal radiotherapy with stereotactic body radiotherapy (SBRT) using helical tomotherapy. The prescription dose of 25.2Gy was applied by conventional radiotherapy. SBRT was performed hypofractionated with a prescription dose of 35Gy in 5 fractions. A dynamic electrocardiogram was performed during every radiation fraction. The implanted aggregates were checked three times a week. Despite partial localization of the active ICD in the radiation field, the tumor was treated without inappropriate shock delivery during radiation treatment and over twelve months afterwards. The reduced tumor size as well as tumor metabolic activity were observed by PET-CT three months after radiation treatment. The patient exhibited no signs of pneumonitis on the last radiological follow-up examination six months after radiotherapy. The reduced dyspnea and cough over the first four months after treatment were observed.In conclusion, tumor shrinkage and temporary clinical improvement of the patient as well as no technical complications of implanted cardiac devices were achieved by the radiation treatment.

No MeSH data available.


Related in: MedlinePlus