Limits...
A photochromic sensor microchip for high-performance multiplex metal ions detection.

Huang Y, Li F, Ye C, Qin M, Ran W, Song Y - Sci Rep (2015)

Bottom Line: It is expected to develop new principles and techniques to achieve high-performance multi-analytes testing with facile sensors.The multi-testing sensor array performed in dark, ultraviolet or visual stimulation, corresponding to different molecular states of spirooxazine metal ions coordination.The facile photochromic microchip contributes a multi-states array sensing method, and will open new opportunities for the development of advanced discriminant analysis for complex analytes.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences.

ABSTRACT
Current multi-analytes chips are limited with requiring numbers of sensors, complex synthesis and compounds screen. It is expected to develop new principles and techniques to achieve high-performance multi-analytes testing with facile sensors. Here, we investigated the correlative multi-states properties of a photochromic sensor (spirooxazine), which is capable of a selective and cross-reactive sensor array for discriminated multi-analytes (11 metal ions) detection by just one sensing compound. The multi-testing sensor array performed in dark, ultraviolet or visual stimulation, corresponding to different molecular states of spirooxazine metal ions coordination. The facile photochromic microchip contributes a multi-states array sensing method, and will open new opportunities for the development of advanced discriminant analysis for complex analytes.

No MeSH data available.


Related in: MedlinePlus

The schematic illustration of the photochromic multi-states sensing for multi-analytes metal ions detection with one spirooxazine sensor.Three states (dark, UV irradiation and Vis irradiation) of spirooxazine-metallic coordination can be obtained by spirooxazine response with metal ions in different irradiation conditions.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4389811&req=5

f1: The schematic illustration of the photochromic multi-states sensing for multi-analytes metal ions detection with one spirooxazine sensor.Three states (dark, UV irradiation and Vis irradiation) of spirooxazine-metallic coordination can be obtained by spirooxazine response with metal ions in different irradiation conditions.

Mentions: There is an increasing need of convenient, rapid, sensitive and high-throughput sensors for target multi-analytes identification in the environmental monitoring1234, aliment safety56, clinical diagnoses7891011121314, and so on1516. Sensor arrays are a verified valid detection method in the area of multi-analytes testing and high-throughput analysis17181920. Currently, a graphene-based ensemble aptamers were exploited to recognize molecular or cellular targets discriminatively10. Cui et al. developed a sensor array assembled from polyionic liquid inverse opaline microspheres to test five anions16. Generally, the sensor array performed the correlative differential analyzing needs large numbers of serial compounds or complicated compound with several recognition groups as sensor, which involves complicated chemical synthesizing and valid compounds screening. Examples include adopting six various 8- hydroxy-quinoline derivants to realize metal ions detection21, designing sensor combining four hydrophobic recognition groups to take molecular diagnostics22, seven sensors utilized a common calix[4]pyrrole receptor to detect 14 carboxylates23. Although the serial sensors own high sensitivity, the high production cost and challenges regarding valid compounds screen restrict their practical applications. These facts call for a reliable sensor to alleviate these concerns for general high-performance multi-analytes detection. Here, we adopt a photochromic material, spirooxazine, to multi-testing sensor array, and utilize the multi-states of the sensing array under stimulations acting the selective and cross-reactive sensing (Fig. 1). This photochromic sensor microchip can actualize eleven various metal ions detection with only one facile sensor, which offers a new strategy to design and develop high-performance multi-testing sensor array.


A photochromic sensor microchip for high-performance multiplex metal ions detection.

Huang Y, Li F, Ye C, Qin M, Ran W, Song Y - Sci Rep (2015)

The schematic illustration of the photochromic multi-states sensing for multi-analytes metal ions detection with one spirooxazine sensor.Three states (dark, UV irradiation and Vis irradiation) of spirooxazine-metallic coordination can be obtained by spirooxazine response with metal ions in different irradiation conditions.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4389811&req=5

f1: The schematic illustration of the photochromic multi-states sensing for multi-analytes metal ions detection with one spirooxazine sensor.Three states (dark, UV irradiation and Vis irradiation) of spirooxazine-metallic coordination can be obtained by spirooxazine response with metal ions in different irradiation conditions.
Mentions: There is an increasing need of convenient, rapid, sensitive and high-throughput sensors for target multi-analytes identification in the environmental monitoring1234, aliment safety56, clinical diagnoses7891011121314, and so on1516. Sensor arrays are a verified valid detection method in the area of multi-analytes testing and high-throughput analysis17181920. Currently, a graphene-based ensemble aptamers were exploited to recognize molecular or cellular targets discriminatively10. Cui et al. developed a sensor array assembled from polyionic liquid inverse opaline microspheres to test five anions16. Generally, the sensor array performed the correlative differential analyzing needs large numbers of serial compounds or complicated compound with several recognition groups as sensor, which involves complicated chemical synthesizing and valid compounds screening. Examples include adopting six various 8- hydroxy-quinoline derivants to realize metal ions detection21, designing sensor combining four hydrophobic recognition groups to take molecular diagnostics22, seven sensors utilized a common calix[4]pyrrole receptor to detect 14 carboxylates23. Although the serial sensors own high sensitivity, the high production cost and challenges regarding valid compounds screen restrict their practical applications. These facts call for a reliable sensor to alleviate these concerns for general high-performance multi-analytes detection. Here, we adopt a photochromic material, spirooxazine, to multi-testing sensor array, and utilize the multi-states of the sensing array under stimulations acting the selective and cross-reactive sensing (Fig. 1). This photochromic sensor microchip can actualize eleven various metal ions detection with only one facile sensor, which offers a new strategy to design and develop high-performance multi-testing sensor array.

Bottom Line: It is expected to develop new principles and techniques to achieve high-performance multi-analytes testing with facile sensors.The multi-testing sensor array performed in dark, ultraviolet or visual stimulation, corresponding to different molecular states of spirooxazine metal ions coordination.The facile photochromic microchip contributes a multi-states array sensing method, and will open new opportunities for the development of advanced discriminant analysis for complex analytes.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences.

ABSTRACT
Current multi-analytes chips are limited with requiring numbers of sensors, complex synthesis and compounds screen. It is expected to develop new principles and techniques to achieve high-performance multi-analytes testing with facile sensors. Here, we investigated the correlative multi-states properties of a photochromic sensor (spirooxazine), which is capable of a selective and cross-reactive sensor array for discriminated multi-analytes (11 metal ions) detection by just one sensing compound. The multi-testing sensor array performed in dark, ultraviolet or visual stimulation, corresponding to different molecular states of spirooxazine metal ions coordination. The facile photochromic microchip contributes a multi-states array sensing method, and will open new opportunities for the development of advanced discriminant analysis for complex analytes.

No MeSH data available.


Related in: MedlinePlus