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Twenty four hour imaging delay improves viability detection by Tl-201 myocardial perfusion scintigraphy.

Koç ZP, Balcı TA, Dağlı N - Rev Bras Cir Cardiovasc (2013 Oct-Dec)

Bottom Line: Viability was found at 52 segments in the early redistribution images and additional 18 segments in the 24 hour delayed redistribution images on segment basis in the evaluation of 510 segments of 30 patients.Three (12%) patients had viable tissue in only 24 hour delayed images.Delayed imaging in Tl-201 MPS is a necessary application for the evaluation of viable tissue according to considerable number of patients with additional improvement in 24 hour images in our study, which is restricted to the patients with myocardial infarct.

View Article: PubMed Central - PubMed

ABSTRACT

Objective: Since twenty-four-hour imaging by Tl-201 myocardial perfusion scintigraphy has been introduced as an effective additional procedure, the aim of this study was to compare this method's result with only rest redistribution procedure in the diagnosis of myocardial viability.

Methods: Thirty patients (Seven female, 23 male; mean: 59.8 ± 10.7, 55.8-63.8 years old) with diagnosis of coronary artery disease were involved in this study. All patients had anamnesis of previous myocardial infarction and/or total occlusion of any main artery in the coronary angiography. Myocardial perfusion scintigraphy with Tl-201 with rest four hour (early) redistribution and 24 hour delayed redistribution protocol were performed to all of the patients. The images were evaluated according to 17 segment basis by an experienced nuclear medicine physician and improvement of a segment by visual interpretation was considered as viable myocardial tissue.

Results: Viability was found at 52 segments in the early redistribution images and additional 18 segments in the 24 hour delayed redistribution images on segment basis in the evaluation of 510 segments of 30 patients. On per patient basis, among the 26 patients who had viable tissue, 14 (54%) had additional improvement in 24 hour delayed images. Three (12%) patients had viable tissue in only 24 hour delayed images.

Conclusion: Delayed imaging in Tl-201 MPS is a necessary application for the evaluation of viable tissue according to considerable number of patients with additional improvement in 24 hour images in our study, which is restricted to the patients with myocardial infarct.

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Short axis, vertical axis, horizontal axis, and bulls eye Tl- 201 MPS images of apatient who has viable tissue only in 24 hour images in septum and anteroseptalwall
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f01: Short axis, vertical axis, horizontal axis, and bulls eye Tl- 201 MPS images of apatient who has viable tissue only in 24 hour images in septum and anteroseptalwall

Mentions: In the evaluation of 510 segments of 30 patients, 52 segments in early redistributionimages and other 18 segments in delayed redistribution images were considered viable ona segment basis. In order to consider the improvement between the rest-redistributionand delayed redistribution images, a significant difference between % scores of thesegments (P<0.05) or improvement of 0-4 scores by at least onedegree was accepted as a threshold. On per patient basis, among the 26 patients who hadviable tissue, 14 (54%) had additional improvement on delayed images. Three (12%)patients had viable tissue only on delayed imaging (Figure 1). Additionally all the patients had global or segmental wall motionabnormalities and mean ejection fraction value obtained from rest redistribution imageswas 30.9 ± 8.9 according to Gated acquisition.


Twenty four hour imaging delay improves viability detection by Tl-201 myocardial perfusion scintigraphy.

Koç ZP, Balcı TA, Dağlı N - Rev Bras Cir Cardiovasc (2013 Oct-Dec)

Short axis, vertical axis, horizontal axis, and bulls eye Tl- 201 MPS images of apatient who has viable tissue only in 24 hour images in septum and anteroseptalwall
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4389430&req=5

f01: Short axis, vertical axis, horizontal axis, and bulls eye Tl- 201 MPS images of apatient who has viable tissue only in 24 hour images in septum and anteroseptalwall
Mentions: In the evaluation of 510 segments of 30 patients, 52 segments in early redistributionimages and other 18 segments in delayed redistribution images were considered viable ona segment basis. In order to consider the improvement between the rest-redistributionand delayed redistribution images, a significant difference between % scores of thesegments (P<0.05) or improvement of 0-4 scores by at least onedegree was accepted as a threshold. On per patient basis, among the 26 patients who hadviable tissue, 14 (54%) had additional improvement on delayed images. Three (12%)patients had viable tissue only on delayed imaging (Figure 1). Additionally all the patients had global or segmental wall motionabnormalities and mean ejection fraction value obtained from rest redistribution imageswas 30.9 ± 8.9 according to Gated acquisition.

Bottom Line: Viability was found at 52 segments in the early redistribution images and additional 18 segments in the 24 hour delayed redistribution images on segment basis in the evaluation of 510 segments of 30 patients.Three (12%) patients had viable tissue in only 24 hour delayed images.Delayed imaging in Tl-201 MPS is a necessary application for the evaluation of viable tissue according to considerable number of patients with additional improvement in 24 hour images in our study, which is restricted to the patients with myocardial infarct.

View Article: PubMed Central - PubMed

ABSTRACT

Objective: Since twenty-four-hour imaging by Tl-201 myocardial perfusion scintigraphy has been introduced as an effective additional procedure, the aim of this study was to compare this method's result with only rest redistribution procedure in the diagnosis of myocardial viability.

Methods: Thirty patients (Seven female, 23 male; mean: 59.8 ± 10.7, 55.8-63.8 years old) with diagnosis of coronary artery disease were involved in this study. All patients had anamnesis of previous myocardial infarction and/or total occlusion of any main artery in the coronary angiography. Myocardial perfusion scintigraphy with Tl-201 with rest four hour (early) redistribution and 24 hour delayed redistribution protocol were performed to all of the patients. The images were evaluated according to 17 segment basis by an experienced nuclear medicine physician and improvement of a segment by visual interpretation was considered as viable myocardial tissue.

Results: Viability was found at 52 segments in the early redistribution images and additional 18 segments in the 24 hour delayed redistribution images on segment basis in the evaluation of 510 segments of 30 patients. On per patient basis, among the 26 patients who had viable tissue, 14 (54%) had additional improvement in 24 hour delayed images. Three (12%) patients had viable tissue in only 24 hour delayed images.

Conclusion: Delayed imaging in Tl-201 MPS is a necessary application for the evaluation of viable tissue according to considerable number of patients with additional improvement in 24 hour images in our study, which is restricted to the patients with myocardial infarct.

Show MeSH
Related in: MedlinePlus