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Seven-day continuous abstinence rate from smoking at 1, 2, or 3 years after the use of varenicline.

Kim JS, Jang JY, Park EH, Lee JY, Gu KM, Jung JW, Choi JC, Shin JW, Park IW, Choi BW, Kim JY - Tuberc Respir Dis (Seoul) (2015)

Bottom Line: Compared to current smokers, successful quitters were older (55.0 years vs. 49.9 years, p=0.01), had better compliance to the 12-week course (27.7 vs. 9.3%, p=0.01), and had taken varenicline longer (10.1 vs. 5.9 weeks, p=0.01).The preferred ways to cease smoking were will-power (48.1%), varenicline (25.9%), nicotine replacement therapy (11.1%), and others (14.9%).Smokers should be encouraged to stick to the proven way for recommended period of time for successful cessation of smoking.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.

ABSTRACT

Background: Varenicline, a selective partial agonist/antagonist of the α4β2 nicotinic receptor, has proven effectiveness for smoking cessation by several randomized, controlled trials. Because few studies have evaluated the long-term efficacy of varenicline, we tried to evaluate the smoking status of varenicline users up to 3 years after the initial prescription of the drug.

Methods: We interviewed varenicline users who were prescribed the drug from June 2007 to May 2010 by telephone, from June 2010 to May 2011.

Results: One-hundred and thirty-three of 250 varenicline users (53.2%) were available for the survey. Seven-day continuous abstinence from smoking was adhered to by 17 of 39 respondents (43.6%) at 1 year, and 11 of 36 (30.6%) and 19 of 58 (32.8%) at 2 and 3 years since the first use of varenicline, respectively. Compared to current smokers, successful quitters were older (55.0 years vs. 49.9 years, p=0.01), had better compliance to the 12-week course (27.7 vs. 9.3%, p=0.01), and had taken varenicline longer (10.1 vs. 5.9 weeks, p=0.01). Fifty-four of 71 current smokers (76.1%) were willing to stop smoking in the near future. The preferred ways to cease smoking were will-power (48.1%), varenicline (25.9%), nicotine replacement therapy (11.1%), and others (14.9%).

Conclusion: Smokers should be encouraged to stick to the proven way for recommended period of time for successful cessation of smoking.

No MeSH data available.


Seven-day continuous abstinence rates from smoking at 1, 2 and 3 years since the first dose of varenicline. Among 133 available respondents, the 7-day continuous abstinence rates were 43.6% (17/39) in the 1st year survey group, 30.6% (11/36) in the 2nd year survey group and 32.8% (19/58) in the 3rd year survey group, respectively.
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Figure 2: Seven-day continuous abstinence rates from smoking at 1, 2 and 3 years since the first dose of varenicline. Among 133 available respondents, the 7-day continuous abstinence rates were 43.6% (17/39) in the 1st year survey group, 30.6% (11/36) in the 2nd year survey group and 32.8% (19/58) in the 3rd year survey group, respectively.

Mentions: Seven-day continuous abstinence from smoking was adhered to by 17 among 39 respondents (43.6%) at 1 year, and 11 out of 36 (30.6%), and 19 among 58 (32.8%) at 2 and 3 years since the first use of varenicline, respectively (Figure 2). There was no significant difference in the 7-day continuous abstinence rate among the three periods surveyed (p=0.429). The average non-smoking period was 6.8±4.42, 16.3±9.41, and 26.9±13.10 months in those who succeeded in smoking cessation at 1, 2, or 3 years since their first prescription of varenicline, respectively.


Seven-day continuous abstinence rate from smoking at 1, 2, or 3 years after the use of varenicline.

Kim JS, Jang JY, Park EH, Lee JY, Gu KM, Jung JW, Choi JC, Shin JW, Park IW, Choi BW, Kim JY - Tuberc Respir Dis (Seoul) (2015)

Seven-day continuous abstinence rates from smoking at 1, 2 and 3 years since the first dose of varenicline. Among 133 available respondents, the 7-day continuous abstinence rates were 43.6% (17/39) in the 1st year survey group, 30.6% (11/36) in the 2nd year survey group and 32.8% (19/58) in the 3rd year survey group, respectively.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4388906&req=5

Figure 2: Seven-day continuous abstinence rates from smoking at 1, 2 and 3 years since the first dose of varenicline. Among 133 available respondents, the 7-day continuous abstinence rates were 43.6% (17/39) in the 1st year survey group, 30.6% (11/36) in the 2nd year survey group and 32.8% (19/58) in the 3rd year survey group, respectively.
Mentions: Seven-day continuous abstinence from smoking was adhered to by 17 among 39 respondents (43.6%) at 1 year, and 11 out of 36 (30.6%), and 19 among 58 (32.8%) at 2 and 3 years since the first use of varenicline, respectively (Figure 2). There was no significant difference in the 7-day continuous abstinence rate among the three periods surveyed (p=0.429). The average non-smoking period was 6.8±4.42, 16.3±9.41, and 26.9±13.10 months in those who succeeded in smoking cessation at 1, 2, or 3 years since their first prescription of varenicline, respectively.

Bottom Line: Compared to current smokers, successful quitters were older (55.0 years vs. 49.9 years, p=0.01), had better compliance to the 12-week course (27.7 vs. 9.3%, p=0.01), and had taken varenicline longer (10.1 vs. 5.9 weeks, p=0.01).The preferred ways to cease smoking were will-power (48.1%), varenicline (25.9%), nicotine replacement therapy (11.1%), and others (14.9%).Smokers should be encouraged to stick to the proven way for recommended period of time for successful cessation of smoking.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.

ABSTRACT

Background: Varenicline, a selective partial agonist/antagonist of the α4β2 nicotinic receptor, has proven effectiveness for smoking cessation by several randomized, controlled trials. Because few studies have evaluated the long-term efficacy of varenicline, we tried to evaluate the smoking status of varenicline users up to 3 years after the initial prescription of the drug.

Methods: We interviewed varenicline users who were prescribed the drug from June 2007 to May 2010 by telephone, from June 2010 to May 2011.

Results: One-hundred and thirty-three of 250 varenicline users (53.2%) were available for the survey. Seven-day continuous abstinence from smoking was adhered to by 17 of 39 respondents (43.6%) at 1 year, and 11 of 36 (30.6%) and 19 of 58 (32.8%) at 2 and 3 years since the first use of varenicline, respectively. Compared to current smokers, successful quitters were older (55.0 years vs. 49.9 years, p=0.01), had better compliance to the 12-week course (27.7 vs. 9.3%, p=0.01), and had taken varenicline longer (10.1 vs. 5.9 weeks, p=0.01). Fifty-four of 71 current smokers (76.1%) were willing to stop smoking in the near future. The preferred ways to cease smoking were will-power (48.1%), varenicline (25.9%), nicotine replacement therapy (11.1%), and others (14.9%).

Conclusion: Smokers should be encouraged to stick to the proven way for recommended period of time for successful cessation of smoking.

No MeSH data available.