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Low grade pulmonary lymphomatoid granulomatosis with an endobronchial mass.

Kim KH, Park J, Yoo JY, Kim MJ, Kim I, Rhee CK, Lee HY - Tuberc Respir Dis (Seoul) (2015)

Bottom Line: Bronchoscopic biopsy was diagnosed with LYG grade 1.After treatment, the endobronchial mass and lung lesions were completely resolved.However, the patient eventually evolved to malignant lymphoma after 1 year.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

ABSTRACT
Lymphomatoid granulomatosis (LYG) is an angiocentric and angiodestructive neoplastic proliferation of B and T lymphocytes commonly involving the lungs. Epstein-Barr virus is commonly detected in lesional cells. We report a case of a 54-year-old female with underlying monoclonal gammopathy of unknown significance who presented with a 4 week history of dyspnea and cough. Computed tomography scan of the chest showed multiple lung nodules as well as endobronchial narrowing causing atelectasis at the left upper lobe. Bronchoscopic findings revealed obstruction at the lingula segment due to endobronchial mass as a rare presentation. Bronchoscopic biopsy was diagnosed with LYG grade 1. After treatment, the endobronchial mass and lung lesions were completely resolved. However, the patient eventually evolved to malignant lymphoma after 1 year.

No MeSH data available.


Related in: MedlinePlus

(A) Initial chest posteroanterior image revealing diffuse patchy and nodular densities in the left lower lung. (B, C) Low dose computed tomography scan of chest on admission showing diffused patchy and nodular densities in both lungs and segmental collapse with proximal endobronchial filling defect in left upper lingula segment.
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Figure 1: (A) Initial chest posteroanterior image revealing diffuse patchy and nodular densities in the left lower lung. (B, C) Low dose computed tomography scan of chest on admission showing diffused patchy and nodular densities in both lungs and segmental collapse with proximal endobronchial filling defect in left upper lingula segment.

Mentions: Initial chest radiograph showed diffuse patchy and nodular densities in the left lower lung (Figure 1A) and a low dose computed tomography of chest revealed variable sized round nodules and segmental collapse with proximal endobronchial filling defect in the left upper lingula segment (Figure 1B, C).


Low grade pulmonary lymphomatoid granulomatosis with an endobronchial mass.

Kim KH, Park J, Yoo JY, Kim MJ, Kim I, Rhee CK, Lee HY - Tuberc Respir Dis (Seoul) (2015)

(A) Initial chest posteroanterior image revealing diffuse patchy and nodular densities in the left lower lung. (B, C) Low dose computed tomography scan of chest on admission showing diffused patchy and nodular densities in both lungs and segmental collapse with proximal endobronchial filling defect in left upper lingula segment.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4388899&req=5

Figure 1: (A) Initial chest posteroanterior image revealing diffuse patchy and nodular densities in the left lower lung. (B, C) Low dose computed tomography scan of chest on admission showing diffused patchy and nodular densities in both lungs and segmental collapse with proximal endobronchial filling defect in left upper lingula segment.
Mentions: Initial chest radiograph showed diffuse patchy and nodular densities in the left lower lung (Figure 1A) and a low dose computed tomography of chest revealed variable sized round nodules and segmental collapse with proximal endobronchial filling defect in the left upper lingula segment (Figure 1B, C).

Bottom Line: Bronchoscopic biopsy was diagnosed with LYG grade 1.After treatment, the endobronchial mass and lung lesions were completely resolved.However, the patient eventually evolved to malignant lymphoma after 1 year.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

ABSTRACT
Lymphomatoid granulomatosis (LYG) is an angiocentric and angiodestructive neoplastic proliferation of B and T lymphocytes commonly involving the lungs. Epstein-Barr virus is commonly detected in lesional cells. We report a case of a 54-year-old female with underlying monoclonal gammopathy of unknown significance who presented with a 4 week history of dyspnea and cough. Computed tomography scan of the chest showed multiple lung nodules as well as endobronchial narrowing causing atelectasis at the left upper lobe. Bronchoscopic findings revealed obstruction at the lingula segment due to endobronchial mass as a rare presentation. Bronchoscopic biopsy was diagnosed with LYG grade 1. After treatment, the endobronchial mass and lung lesions were completely resolved. However, the patient eventually evolved to malignant lymphoma after 1 year.

No MeSH data available.


Related in: MedlinePlus