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Laparoscopic assistance for primary transanal pull-through in Hirschsprung's disease: a systematic review and meta-analysis.

Thomson D, Allin B, Long AM, Bradnock T, Walker G, Knight M - BMJ Open (2015)

Bottom Line: There were no significant differences identified between TTERPT and LAPT for incidence of postoperative enterocolitis (OR=0.78, 95% CI 0.44 to 1.38, p=0.39), faecal incontinence (OR=0.44, 95% CI 0.09 to 2.20, p=0.32) or constipation (OR=0.84, 95% CI 0.32 to 2.17, p=0.71).This meta-analysis did not find any evidence to suggest a higher rate of enterocolitis, incontinence or constipation following TTERPT compared with LAPT.PROSPERO registry- CRD42013005698.

View Article: PubMed Central - PubMed

Affiliation: National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK.

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PRISMA flow chart summarising study selection process.
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BMJOPEN2014006063F1: PRISMA flow chart summarising study selection process.

Mentions: A total of 2107 records were screened, of which 41 studies potentially met the eligibility criteria (figure 1). Thirty-one studies were excluded because there was no comparative study arm. Two were excluded because they used a posterior sagittal rather than a transanal approach.2021 One study was excluded because it used a laparoscopic Duhamel-type anastomosis22 and one study because infants undergoing a staged procedure were pooled with primary procedure results.23 Data were sought from the authors of two studies that pooled transabdominal and laparoscopic-assisted procedures.24 Data were available and generously provided by the authors of one of these studies.25 Four further retrospective observational studies were eligible for inclusion in the final review.26–28


Laparoscopic assistance for primary transanal pull-through in Hirschsprung's disease: a systematic review and meta-analysis.

Thomson D, Allin B, Long AM, Bradnock T, Walker G, Knight M - BMJ Open (2015)

PRISMA flow chart summarising study selection process.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4386272&req=5

BMJOPEN2014006063F1: PRISMA flow chart summarising study selection process.
Mentions: A total of 2107 records were screened, of which 41 studies potentially met the eligibility criteria (figure 1). Thirty-one studies were excluded because there was no comparative study arm. Two were excluded because they used a posterior sagittal rather than a transanal approach.2021 One study was excluded because it used a laparoscopic Duhamel-type anastomosis22 and one study because infants undergoing a staged procedure were pooled with primary procedure results.23 Data were sought from the authors of two studies that pooled transabdominal and laparoscopic-assisted procedures.24 Data were available and generously provided by the authors of one of these studies.25 Four further retrospective observational studies were eligible for inclusion in the final review.26–28

Bottom Line: There were no significant differences identified between TTERPT and LAPT for incidence of postoperative enterocolitis (OR=0.78, 95% CI 0.44 to 1.38, p=0.39), faecal incontinence (OR=0.44, 95% CI 0.09 to 2.20, p=0.32) or constipation (OR=0.84, 95% CI 0.32 to 2.17, p=0.71).This meta-analysis did not find any evidence to suggest a higher rate of enterocolitis, incontinence or constipation following TTERPT compared with LAPT.PROSPERO registry- CRD42013005698.

View Article: PubMed Central - PubMed

Affiliation: National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK.

Show MeSH
Related in: MedlinePlus