Laparoscopic assistance for primary transanal pull-through in Hirschsprung's disease: a systematic review and meta-analysis.
Bottom Line: There were no significant differences identified between TTERPT and LAPT for incidence of postoperative enterocolitis (OR=0.78, 95% CI 0.44 to 1.38, p=0.39), faecal incontinence (OR=0.44, 95% CI 0.09 to 2.20, p=0.32) or constipation (OR=0.84, 95% CI 0.32 to 2.17, p=0.71).This meta-analysis did not find any evidence to suggest a higher rate of enterocolitis, incontinence or constipation following TTERPT compared with LAPT.PROSPERO registry- CRD42013005698.
Affiliation: National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK.Show MeSH
Related in: MedlinePlus
Mentions: A total of 2107 records were screened, of which 41 studies potentially met the eligibility criteria (figure 1). Thirty-one studies were excluded because there was no comparative study arm. Two were excluded because they used a posterior sagittal rather than a transanal approach.2021 One study was excluded because it used a laparoscopic Duhamel-type anastomosis22 and one study because infants undergoing a staged procedure were pooled with primary procedure results.23 Data were sought from the authors of two studies that pooled transabdominal and laparoscopic-assisted procedures.24 Data were available and generously provided by the authors of one of these studies.25 Four further retrospective observational studies were eligible for inclusion in the final review.26–28
Affiliation: National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK.