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Solid pseudopapillary tumor of the pancreas in a patient with cervical cancer: relation of E-cadherin/β-catenin adhesion complex in their carcinogenesis.

Vijay A, Ram L, Mathew RK, Chawdhery MZ - J Surg Case Rep (2015)

Bottom Line: A 38-year-old married woman, who had undergone brachytherapy, radiotherapy and chemotherapy for cervical cancer in Philippines in 2011, was admitted to our hospital after follow-up CT scan of abdomen in 2012 revealed a lesion in the tail of pancreas.The pathological diagnosis was SPT of pancreas.We suspect that the concurrent SPT pancreas and cervical cancer in this woman were triggered by a primary insult, a process in which E-cadherin/β-catenin/Wnt-signaling pathway played important roles.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of General Surgery, Hamad Medical Corporation, Doha, Qatar dradarshvijay@hotmail.com.

No MeSH data available.


Related in: MedlinePlus

MRI showing lesion at tail of pancreas.
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RJV034F1: MRI showing lesion at tail of pancreas.

Mentions: A 38-year-old married woman, who had undergone brachytherapy, radiotherapy and chemotherapy for cervical cancer in the Philippines in the year 2011, was admitted to our hospital after a follow-up CT scan of the abdomen in 2012 revealed a lesion in the tail of pancreas which on subsequent MRI scan was diagnosed as benign intraductal papillary mucinous neoplasm measuring 5.1 × 4.6 cm (Fig. 1). Physical examination revealed no abnormal findings. Tumor markers including CA 19-9 and CA 125 were within normal limits. Cervical smear was negative for malignancy. The patient underwent distal pancreatectomy and splenectomy. Histopathological examination showed solid pseudopapillary tumor of the pancreas (Fig. 2). Postoperatively she developed unilateral lower lobe consolidation. She recovered smoothly and was discharged 8 days after resection.Figure 1:


Solid pseudopapillary tumor of the pancreas in a patient with cervical cancer: relation of E-cadherin/β-catenin adhesion complex in their carcinogenesis.

Vijay A, Ram L, Mathew RK, Chawdhery MZ - J Surg Case Rep (2015)

MRI showing lesion at tail of pancreas.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4385891&req=5

RJV034F1: MRI showing lesion at tail of pancreas.
Mentions: A 38-year-old married woman, who had undergone brachytherapy, radiotherapy and chemotherapy for cervical cancer in the Philippines in the year 2011, was admitted to our hospital after a follow-up CT scan of the abdomen in 2012 revealed a lesion in the tail of pancreas which on subsequent MRI scan was diagnosed as benign intraductal papillary mucinous neoplasm measuring 5.1 × 4.6 cm (Fig. 1). Physical examination revealed no abnormal findings. Tumor markers including CA 19-9 and CA 125 were within normal limits. Cervical smear was negative for malignancy. The patient underwent distal pancreatectomy and splenectomy. Histopathological examination showed solid pseudopapillary tumor of the pancreas (Fig. 2). Postoperatively she developed unilateral lower lobe consolidation. She recovered smoothly and was discharged 8 days after resection.Figure 1:

Bottom Line: A 38-year-old married woman, who had undergone brachytherapy, radiotherapy and chemotherapy for cervical cancer in Philippines in 2011, was admitted to our hospital after follow-up CT scan of abdomen in 2012 revealed a lesion in the tail of pancreas.The pathological diagnosis was SPT of pancreas.We suspect that the concurrent SPT pancreas and cervical cancer in this woman were triggered by a primary insult, a process in which E-cadherin/β-catenin/Wnt-signaling pathway played important roles.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of General Surgery, Hamad Medical Corporation, Doha, Qatar dradarshvijay@hotmail.com.

No MeSH data available.


Related in: MedlinePlus