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Sjögren's Syndrome: A Case Study.

Jadhav S, Jadhav A, Thopte S, Marathe S, Vhathakar P, Chivte P, Jamkhande A - J Int Oral Health (2015)

Bottom Line: It may occur in two forms - Primary and secondary, which is associated with another autoimmune disease, most commonly rheumatoid arthritis.The classification requires four of the six items, one of which must be positive minor salivary gland biopsy or a positive antibody test.Early diagnosis is important to prevent further complications.

View Article: PubMed Central - PubMed

Affiliation: Assistant Professor, Department of Oral Medicine and Radiology, Bharati Vidyapeeth Deemed University Dental College & Hospital, Pune, Maharashtra, India.

ABSTRACT
Sjögren syndrome is chronic, systemic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands. It is an elaborate involvement of the lacrimal and salivary glands, which eventually lead to keratoconjunctivitis sicca and xerostomia. It may occur in two forms - Primary and secondary, which is associated with another autoimmune disease, most commonly rheumatoid arthritis. Numerous criteria were proposed for diagnosis of Sjögren syndrome. Most widely accepted are American and European group developed international classification criteria for Sjögrens syndrome. These criteria include ocular symptoms, oral symptoms, ocular signs, histopathology, salivary gland involvement and sialography. The classification requires four of the six items, one of which must be positive minor salivary gland biopsy or a positive antibody test. Early diagnosis is important to prevent further complications. The aim of this paper is to emphasis on oral changes, advanced diagnosis, and management of Sjögren's syndrome.

No MeSH data available.


Related in: MedlinePlus

Sialography showing diffuse foci of sialectasis.
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Figure 5: Sialography showing diffuse foci of sialectasis.

Mentions: Culture and sensitivity test showed organism isolated Escherichia coli grown. Complete hemogram showed increased erythrocyte sedimentation rate. Schirmer test and Rose Bengal dye test was positive. Serum immunoglobulin – SS-A RO positive for Sjögrens syndrome. RA factor was positive for rheumatoid arthritis. Ultrasonography shows bilateral submandibular and parotid gland enlargement with multiple hypoechoic lesions within showing very high vascularity, likely to present systemic disorder like Sjögren’s syndrome. Sialography shows diffuse foci of sialectasis (Figure 5). Incisional biopsy of lower lip was not done because the patient was not ready for the biopsy.


Sjögren's Syndrome: A Case Study.

Jadhav S, Jadhav A, Thopte S, Marathe S, Vhathakar P, Chivte P, Jamkhande A - J Int Oral Health (2015)

Sialography showing diffuse foci of sialectasis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4385732&req=5

Figure 5: Sialography showing diffuse foci of sialectasis.
Mentions: Culture and sensitivity test showed organism isolated Escherichia coli grown. Complete hemogram showed increased erythrocyte sedimentation rate. Schirmer test and Rose Bengal dye test was positive. Serum immunoglobulin – SS-A RO positive for Sjögrens syndrome. RA factor was positive for rheumatoid arthritis. Ultrasonography shows bilateral submandibular and parotid gland enlargement with multiple hypoechoic lesions within showing very high vascularity, likely to present systemic disorder like Sjögren’s syndrome. Sialography shows diffuse foci of sialectasis (Figure 5). Incisional biopsy of lower lip was not done because the patient was not ready for the biopsy.

Bottom Line: It may occur in two forms - Primary and secondary, which is associated with another autoimmune disease, most commonly rheumatoid arthritis.The classification requires four of the six items, one of which must be positive minor salivary gland biopsy or a positive antibody test.Early diagnosis is important to prevent further complications.

View Article: PubMed Central - PubMed

Affiliation: Assistant Professor, Department of Oral Medicine and Radiology, Bharati Vidyapeeth Deemed University Dental College & Hospital, Pune, Maharashtra, India.

ABSTRACT
Sjögren syndrome is chronic, systemic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands. It is an elaborate involvement of the lacrimal and salivary glands, which eventually lead to keratoconjunctivitis sicca and xerostomia. It may occur in two forms - Primary and secondary, which is associated with another autoimmune disease, most commonly rheumatoid arthritis. Numerous criteria were proposed for diagnosis of Sjögren syndrome. Most widely accepted are American and European group developed international classification criteria for Sjögrens syndrome. These criteria include ocular symptoms, oral symptoms, ocular signs, histopathology, salivary gland involvement and sialography. The classification requires four of the six items, one of which must be positive minor salivary gland biopsy or a positive antibody test. Early diagnosis is important to prevent further complications. The aim of this paper is to emphasis on oral changes, advanced diagnosis, and management of Sjögren's syndrome.

No MeSH data available.


Related in: MedlinePlus