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Synthesis of novel peptide dendrimers PDL-GB2 and PDL-G2.

Yunzhu L, Lingling W, Qingrong Q - ScientificWorldJournal (2015)

Bottom Line: So it is valuable to study.In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit.And the structures were identified by 1HNMR, 13CNMR, MS, and elemental analysis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacy, Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China ; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, China.

ABSTRACT
Peptide dendrimers are a novel type of macromolecules with precise structure, which can be used as drug target vector and controlled-release carrier. So it is valuable to study. In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit. And the structures were identified by 1HNMR, 13CNMR, MS, and elemental analysis.

No MeSH data available.


Synthesis of PDL-C4.
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Related In: Results  -  Collection


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sch2: Synthesis of PDL-C4.

Mentions: Melting point was measured through capillary tube method. Mass measurement was made by Walters Q-TOF Premier type. NMR spectra were obtained on Varian Unity INOVA NMR measurement using TMS as the internal standard. Elemental analysis was carried out on CARLO-ERBA 1106 type instrument.


Synthesis of novel peptide dendrimers PDL-GB2 and PDL-G2.

Yunzhu L, Lingling W, Qingrong Q - ScientificWorldJournal (2015)

Synthesis of PDL-C4.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4385662&req=5

sch2: Synthesis of PDL-C4.
Mentions: Melting point was measured through capillary tube method. Mass measurement was made by Walters Q-TOF Premier type. NMR spectra were obtained on Varian Unity INOVA NMR measurement using TMS as the internal standard. Elemental analysis was carried out on CARLO-ERBA 1106 type instrument.

Bottom Line: So it is valuable to study.In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit.And the structures were identified by 1HNMR, 13CNMR, MS, and elemental analysis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacy, Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China ; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, China.

ABSTRACT
Peptide dendrimers are a novel type of macromolecules with precise structure, which can be used as drug target vector and controlled-release carrier. So it is valuable to study. In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit. And the structures were identified by 1HNMR, 13CNMR, MS, and elemental analysis.

No MeSH data available.