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Synthesis of novel peptide dendrimers PDL-GB2 and PDL-G2.

Yunzhu L, Lingling W, Qingrong Q - ScientificWorldJournal (2015)

Bottom Line: So it is valuable to study.In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit.And the structures were identified by 1HNMR, 13CNMR, MS, and elemental analysis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacy, Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China ; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, China.

ABSTRACT
Peptide dendrimers are a novel type of macromolecules with precise structure, which can be used as drug target vector and controlled-release carrier. So it is valuable to study. In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit. And the structures were identified by 1HNMR, 13CNMR, MS, and elemental analysis.

No MeSH data available.


The classic dendrimer.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4385662&req=5

fig1: The classic dendrimer.

Mentions: Dendrimers are a sort of high-molecular compound with peculiar properties which possess high symmetry in geometry morphology, precise molecular structure, and a number of functional groups (see Figure 1). Besides, the cavities and the branch length of the dendrimers can be controlled well.


Synthesis of novel peptide dendrimers PDL-GB2 and PDL-G2.

Yunzhu L, Lingling W, Qingrong Q - ScientificWorldJournal (2015)

The classic dendrimer.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4385662&req=5

fig1: The classic dendrimer.
Mentions: Dendrimers are a sort of high-molecular compound with peculiar properties which possess high symmetry in geometry morphology, precise molecular structure, and a number of functional groups (see Figure 1). Besides, the cavities and the branch length of the dendrimers can be controlled well.

Bottom Line: So it is valuable to study.In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit.And the structures were identified by 1HNMR, 13CNMR, MS, and elemental analysis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacy, Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China ; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, China.

ABSTRACT
Peptide dendrimers are a novel type of macromolecules with precise structure, which can be used as drug target vector and controlled-release carrier. So it is valuable to study. In this paper, novel peptide dendrimers PDL-GB2 and PDL-G2 were prepared according to divergent procedure with four-orientation molecule as the core and L-lysine as the branch unit. And the structures were identified by 1HNMR, 13CNMR, MS, and elemental analysis.

No MeSH data available.