Limits...
Primary antiphospholipid syndrome associated with pneumonia: a case report of a 16-year-old male patient.

Yilmaz S, Topcu F, Selimoglu Sen H, Yildirim Y, Yilmaz Z, Kara AV, Akgul Ozmen C - Case Rep Pulmonol (2015)

Bottom Line: The patient was evaluated as primary APS since another etiology that could explain PTE was not found.Primary APS is a rare disease in children along with adolescents, compared with APS associated with other systemic autoimmune diseases.The patient initially had pneumonia but later developed PTE and thrombocytopenia.

View Article: PubMed Central - PubMed

Affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, 21100 Diyarbakir, Turkey.

ABSTRACT
Antiphospholipid syndrome (APS) is an autoimmune disease characterised by arterial and/or venous thrombosis and/or recurrent pregnancy loss in the presence of antiphospholipid (APL) antibodies. It is evaluated as APS when it develops associated with other systemic autoimmune diseases or primary APS if there is no concomitant disorder. In this study, we present a case of a 16-year-old male patient with primary APS. The patient was admitted with presumptive diagnosis of pneumonia, but multiple pulmonary thromboembolism (PTE) was observed on computerized tomography (CT) pulmonary angiography. APL antibodies positivity and thrombocytopenia developed in our patient. The patient was evaluated as primary APS since another etiology that could explain PTE was not found. Primary APS is a rare disease in children along with adolescents, compared with APS associated with other systemic autoimmune diseases. We present here a young male patient with primary APS and PTE to contribute to the literature. The patient initially had pneumonia but later developed PTE and thrombocytopenia.

No MeSH data available.


Related in: MedlinePlus

Consolidation areas in the lower lobe of right lung, upper-lower lobe of left lung, and lingula were observed in first drawn contrast enhanced computed tomography.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4385638&req=5

fig1: Consolidation areas in the lower lobe of right lung, upper-lower lobe of left lung, and lingula were observed in first drawn contrast enhanced computed tomography.

Mentions: The first contrast-enhanced thorax tomography of the patient revealed widespread consolidation and ground-glass appearance in the lower lobe of the right lung and consolidation areas that occurred by merging of nodules in the apicoposterior part of the left lung. Atelectasis and increased density due to consolidation were observed in the upper lobe lingula and lower lobe of the left lung. Patient was evaluated as pneumonia (Figure 1). Pulmonary embolism was not detected in this tomography. Antibiotics and general supportive therapy were started. Control thorax tomography was performed 25 days after the treatment since there was no improvement in the patient's cough, chest pain, and radiological status. Multiple hypodense filling defects were observed in the right main pulmonary artery and branches of left pulmonary artery at control computerized tomographic pulmonary angiography, and it was then evaluated as PTE. Patchy areas of consolidation in the lower lobes of both lungs were evaluated as necrosis and ground glass areas of the superior of the upper and lower lobes were evaluated as infiltration (Figure 2).


Primary antiphospholipid syndrome associated with pneumonia: a case report of a 16-year-old male patient.

Yilmaz S, Topcu F, Selimoglu Sen H, Yildirim Y, Yilmaz Z, Kara AV, Akgul Ozmen C - Case Rep Pulmonol (2015)

Consolidation areas in the lower lobe of right lung, upper-lower lobe of left lung, and lingula were observed in first drawn contrast enhanced computed tomography.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4385638&req=5

fig1: Consolidation areas in the lower lobe of right lung, upper-lower lobe of left lung, and lingula were observed in first drawn contrast enhanced computed tomography.
Mentions: The first contrast-enhanced thorax tomography of the patient revealed widespread consolidation and ground-glass appearance in the lower lobe of the right lung and consolidation areas that occurred by merging of nodules in the apicoposterior part of the left lung. Atelectasis and increased density due to consolidation were observed in the upper lobe lingula and lower lobe of the left lung. Patient was evaluated as pneumonia (Figure 1). Pulmonary embolism was not detected in this tomography. Antibiotics and general supportive therapy were started. Control thorax tomography was performed 25 days after the treatment since there was no improvement in the patient's cough, chest pain, and radiological status. Multiple hypodense filling defects were observed in the right main pulmonary artery and branches of left pulmonary artery at control computerized tomographic pulmonary angiography, and it was then evaluated as PTE. Patchy areas of consolidation in the lower lobes of both lungs were evaluated as necrosis and ground glass areas of the superior of the upper and lower lobes were evaluated as infiltration (Figure 2).

Bottom Line: The patient was evaluated as primary APS since another etiology that could explain PTE was not found.Primary APS is a rare disease in children along with adolescents, compared with APS associated with other systemic autoimmune diseases.The patient initially had pneumonia but later developed PTE and thrombocytopenia.

View Article: PubMed Central - PubMed

Affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, 21100 Diyarbakir, Turkey.

ABSTRACT
Antiphospholipid syndrome (APS) is an autoimmune disease characterised by arterial and/or venous thrombosis and/or recurrent pregnancy loss in the presence of antiphospholipid (APL) antibodies. It is evaluated as APS when it develops associated with other systemic autoimmune diseases or primary APS if there is no concomitant disorder. In this study, we present a case of a 16-year-old male patient with primary APS. The patient was admitted with presumptive diagnosis of pneumonia, but multiple pulmonary thromboembolism (PTE) was observed on computerized tomography (CT) pulmonary angiography. APL antibodies positivity and thrombocytopenia developed in our patient. The patient was evaluated as primary APS since another etiology that could explain PTE was not found. Primary APS is a rare disease in children along with adolescents, compared with APS associated with other systemic autoimmune diseases. We present here a young male patient with primary APS and PTE to contribute to the literature. The patient initially had pneumonia but later developed PTE and thrombocytopenia.

No MeSH data available.


Related in: MedlinePlus