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Study of parasitic resistance effects in nanowire and nanoribbon biosensors.

Zeimpekis I, Sun K, Hu C, Thomas O, de Planque MR, Chong HM, Morgan H, Ashburn P - Nanoscale Res Lett (2015)

Bottom Line: Measurements of pH with polysilicon nanoribbon biosensors are used to demonstrate a reduction in sensitivity as the sensor length is reduced.These results are interpreted using a simple empirical model, which is also used to demonstrate how the sensitivity degradation can be alleviated by a suitable choice of sensor window length.Furthermore, a differential sensor design is proposed that eliminates the detrimental effects of parasitic resistance.

View Article: PubMed Central - PubMed

Affiliation: Zepler Institute, School of Electronics & Computer Science, University of Southampton, Southampton, SO17 1BJ UK.

ABSTRACT
In this work, we investigate sensor design approaches for eliminating the effects of parasitic resistance in nanowire and nanoribbon biosensors. Measurements of pH with polysilicon nanoribbon biosensors are used to demonstrate a reduction in sensitivity as the sensor length is reduced. The sensitivity (normalised conductance change) is reduced from 11% to 5.5% for a pH change from 9 to 3 as the sensing window length is reduced from 51 to 11 μm. These results are interpreted using a simple empirical model, which is also used to demonstrate how the sensitivity degradation can be alleviated by a suitable choice of sensor window length. Furthermore, a differential sensor design is proposed that eliminates the detrimental effects of parasitic resistance. Measurements on the differential sensor give a sensitivity of 15%, which is in good agreement with the predicted maximum sensitivity obtained from modeling.

No MeSH data available.


Modeled normalized conductance change (sensitivity) as a function of sensing window length at different values of pH. The graph also includes measured data from two devices with sensing window lengths of 11 and 31 μm.
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Fig3: Modeled normalized conductance change (sensitivity) as a function of sensing window length at different values of pH. The graph also includes measured data from two devices with sensing window lengths of 11 and 31 μm.

Mentions: Figure 3 shows the modeled sensitivity as a function of sensing window length (solid lines) calculated with parameters obtained from measurements on a sensor with a sensing window length of 51 μm. The measured sensitivities of two devices with sensing window lengths of 11 and 31 μm are also presented (points). The curves closely match the measured data indicating that the experimental data can be modeled with reasonable accuracy.Figure 3


Study of parasitic resistance effects in nanowire and nanoribbon biosensors.

Zeimpekis I, Sun K, Hu C, Thomas O, de Planque MR, Chong HM, Morgan H, Ashburn P - Nanoscale Res Lett (2015)

Modeled normalized conductance change (sensitivity) as a function of sensing window length at different values of pH. The graph also includes measured data from two devices with sensing window lengths of 11 and 31 μm.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4385057&req=5

Fig3: Modeled normalized conductance change (sensitivity) as a function of sensing window length at different values of pH. The graph also includes measured data from two devices with sensing window lengths of 11 and 31 μm.
Mentions: Figure 3 shows the modeled sensitivity as a function of sensing window length (solid lines) calculated with parameters obtained from measurements on a sensor with a sensing window length of 51 μm. The measured sensitivities of two devices with sensing window lengths of 11 and 31 μm are also presented (points). The curves closely match the measured data indicating that the experimental data can be modeled with reasonable accuracy.Figure 3

Bottom Line: Measurements of pH with polysilicon nanoribbon biosensors are used to demonstrate a reduction in sensitivity as the sensor length is reduced.These results are interpreted using a simple empirical model, which is also used to demonstrate how the sensitivity degradation can be alleviated by a suitable choice of sensor window length.Furthermore, a differential sensor design is proposed that eliminates the detrimental effects of parasitic resistance.

View Article: PubMed Central - PubMed

Affiliation: Zepler Institute, School of Electronics & Computer Science, University of Southampton, Southampton, SO17 1BJ UK.

ABSTRACT
In this work, we investigate sensor design approaches for eliminating the effects of parasitic resistance in nanowire and nanoribbon biosensors. Measurements of pH with polysilicon nanoribbon biosensors are used to demonstrate a reduction in sensitivity as the sensor length is reduced. The sensitivity (normalised conductance change) is reduced from 11% to 5.5% for a pH change from 9 to 3 as the sensing window length is reduced from 51 to 11 μm. These results are interpreted using a simple empirical model, which is also used to demonstrate how the sensitivity degradation can be alleviated by a suitable choice of sensor window length. Furthermore, a differential sensor design is proposed that eliminates the detrimental effects of parasitic resistance. Measurements on the differential sensor give a sensitivity of 15%, which is in good agreement with the predicted maximum sensitivity obtained from modeling.

No MeSH data available.