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The benefits of preincision ropivacaine infiltration for reducing postoperative pain after robotic bilateral axillo-breast approach thyroidectomy: a prospective, randomized, double-blind, placebo-controlled study.

Kang KH, Kim BS, Kang H - Ann Surg Treat Res (2015)

Bottom Line: Fentanyl use for analgesia and BHC were also significantly lower in group L compared with group C during the first postoperative 6 and 2 hours, respectively (P < 0.05).The total consumption of fentanyl was significantly lower in group L than in group C (P = 0.009).No significant differences were noted for baseline, postoperative mean BP, or HR.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.

ABSTRACT

Purpose: The aim of this study was to evaluate the effects of preoperative ropivacaine infiltration in patients undergoing robotic thyroidectomy using the bilateral axillary breast approach method.

Methods: Using a randomized, double-blind study design, 34 consecutive female patients who underwent robotic thyroidectomy were randomly assigned to receive local infiltration to the skin flap site using either only 0.9% saline solution, 3 mL/kg (group C, n = 17) or 0.1% ropivacaine with saline, 3 mg/kg (group L, n = 17). Local anesthetic was administered prior to skin incision after the induction of general anesthesia. Postoperative pain was rated at 2, 6, 18, 30, 42, and 66 hours postoperatively by visual analogue scale (VAS) score. The bottom hit counts (BHC) from patient controlled analgesia and fentanyl consumption were evaluated. CRP levels, mean blood pressure (BP), and heart rate (HR) were also evaluated.

Results: VAS pain scores were significantly lower in group L than in group C from 2 to 42 hours (P < 0.05). Fentanyl use for analgesia and BHC were also significantly lower in group L compared with group C during the first postoperative 6 and 2 hours, respectively (P < 0.05). The total consumption of fentanyl was significantly lower in group L than in group C (P = 0.009). No significant differences were noted for baseline, postoperative mean BP, or HR.

Conclusion: Preoperative infiltration using ropivacaine with saline to all flap sites is a safe and effective method for reducing postoperative pain and postoperative fentanyl consumption in patients with robotic thyroidectomy.

No MeSH data available.


Related in: MedlinePlus

Additional fentanyl use was lower in the ropivacaine group than in the control group at postoperative 2 and 6 hours. Values are expressed as mean ± standard error. Group C, saline infiltration group; group L, 0.1% ropivacaine infiltration group. *P < 0.05 compared with group C.
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Figure 3: Additional fentanyl use was lower in the ropivacaine group than in the control group at postoperative 2 and 6 hours. Values are expressed as mean ± standard error. Group C, saline infiltration group; group L, 0.1% ropivacaine infiltration group. *P < 0.05 compared with group C.

Mentions: Fentanyl use for analgesia and BHC was significantly lower in group L than in group C during the first postoperative 6 and 2 hours, respectively (Figs. 3 and 4). The clinical differences between the two groups gradually diminished over time. The total fentanyl consumption and total BHC were lower in group L than group C (Table 2). The postoperative CRP levels were not statistically significant between the two groups (Fig. 5). No significant differences were noted for baseline and postoperative mean BP and HR. There were no significant differences between the two groups in postoperative drainage amount, the length of hospital stay, or complications such as PONV (Table 3).


The benefits of preincision ropivacaine infiltration for reducing postoperative pain after robotic bilateral axillo-breast approach thyroidectomy: a prospective, randomized, double-blind, placebo-controlled study.

Kang KH, Kim BS, Kang H - Ann Surg Treat Res (2015)

Additional fentanyl use was lower in the ropivacaine group than in the control group at postoperative 2 and 6 hours. Values are expressed as mean ± standard error. Group C, saline infiltration group; group L, 0.1% ropivacaine infiltration group. *P < 0.05 compared with group C.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4384283&req=5

Figure 3: Additional fentanyl use was lower in the ropivacaine group than in the control group at postoperative 2 and 6 hours. Values are expressed as mean ± standard error. Group C, saline infiltration group; group L, 0.1% ropivacaine infiltration group. *P < 0.05 compared with group C.
Mentions: Fentanyl use for analgesia and BHC was significantly lower in group L than in group C during the first postoperative 6 and 2 hours, respectively (Figs. 3 and 4). The clinical differences between the two groups gradually diminished over time. The total fentanyl consumption and total BHC were lower in group L than group C (Table 2). The postoperative CRP levels were not statistically significant between the two groups (Fig. 5). No significant differences were noted for baseline and postoperative mean BP and HR. There were no significant differences between the two groups in postoperative drainage amount, the length of hospital stay, or complications such as PONV (Table 3).

Bottom Line: Fentanyl use for analgesia and BHC were also significantly lower in group L compared with group C during the first postoperative 6 and 2 hours, respectively (P < 0.05).The total consumption of fentanyl was significantly lower in group L than in group C (P = 0.009).No significant differences were noted for baseline, postoperative mean BP, or HR.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.

ABSTRACT

Purpose: The aim of this study was to evaluate the effects of preoperative ropivacaine infiltration in patients undergoing robotic thyroidectomy using the bilateral axillary breast approach method.

Methods: Using a randomized, double-blind study design, 34 consecutive female patients who underwent robotic thyroidectomy were randomly assigned to receive local infiltration to the skin flap site using either only 0.9% saline solution, 3 mL/kg (group C, n = 17) or 0.1% ropivacaine with saline, 3 mg/kg (group L, n = 17). Local anesthetic was administered prior to skin incision after the induction of general anesthesia. Postoperative pain was rated at 2, 6, 18, 30, 42, and 66 hours postoperatively by visual analogue scale (VAS) score. The bottom hit counts (BHC) from patient controlled analgesia and fentanyl consumption were evaluated. CRP levels, mean blood pressure (BP), and heart rate (HR) were also evaluated.

Results: VAS pain scores were significantly lower in group L than in group C from 2 to 42 hours (P < 0.05). Fentanyl use for analgesia and BHC were also significantly lower in group L compared with group C during the first postoperative 6 and 2 hours, respectively (P < 0.05). The total consumption of fentanyl was significantly lower in group L than in group C (P = 0.009). No significant differences were noted for baseline, postoperative mean BP, or HR.

Conclusion: Preoperative infiltration using ropivacaine with saline to all flap sites is a safe and effective method for reducing postoperative pain and postoperative fentanyl consumption in patients with robotic thyroidectomy.

No MeSH data available.


Related in: MedlinePlus