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Preparation and preliminary dialysis performance research of polyvinylidene fluoride hollow fiber membranes.

Zhang Q, Lu X, Liu J, Zhao L - Membranes (Basel) (2015)

Bottom Line: The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence.The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea.The clearance rate of LZM was 66.8% and urea was 87.7%.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, China. haiyang19802005@163.com.

ABSTRACT
In this study, the separation properties of Polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were improved by optimizing membrane morphology and structure. The results showed that the PVDF membrane had better mechanical and separation properties than Fresenius Polysulfone High-Flux (F60S) membrane. The PVDF membrane tensile stress at break, tensile elongation and bursting pressure were 11.3 MPa, 395% and 0.625 MPa, respectively. Ultrafiltration (UF) flux of pure water reached 108.2 L∙h-1∙m-2 and rejection of Albumin from bovine serum was 82.3%. The PVDF dialyzers were prepared by centrifugal casting. The influences of membrane area and simulate fluid flow rate on dialysis performance were investigated. The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence. The high-flux PVDF dialyzer UF coefficient reached 62.6 mL/h/mmHg. The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea. The clearance rate of LZM was 66.8% and urea was 87.7%.

No MeSH data available.


Related in: MedlinePlus

The SEM morphologies of different PVDF membranes, the labels M-14.8, M-16.8, M-3 and M-20.8 are membranes with PEG content 14.8, 16.8, 18.8 and 20.8 wt %.
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membranes-05-00120-f004: The SEM morphologies of different PVDF membranes, the labels M-14.8, M-16.8, M-3 and M-20.8 are membranes with PEG content 14.8, 16.8, 18.8 and 20.8 wt %.

Mentions: The PVDF hollow fiber membranes SEM morphologies with different PEG content are shown in Figure 4. There was typical asymmetric structure in different PVDF membranes. The structure was made of a skin layer; an intermediate layer with finger-like structure; and a bottom layer with fully developed macrospores [22]. Finger-like structure dominates the cross section in M-14.8 and M-16.8 membranes. The sponge-structure in M-3 membrane becomes more and more obvious when compared to other membranes that have more finger-like structure. There are some defective structures in M-20.8 membrane. That can be explained by the solvent and non-solvent diffusion rate.


Preparation and preliminary dialysis performance research of polyvinylidene fluoride hollow fiber membranes.

Zhang Q, Lu X, Liu J, Zhao L - Membranes (Basel) (2015)

The SEM morphologies of different PVDF membranes, the labels M-14.8, M-16.8, M-3 and M-20.8 are membranes with PEG content 14.8, 16.8, 18.8 and 20.8 wt %.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4384094&req=5

membranes-05-00120-f004: The SEM morphologies of different PVDF membranes, the labels M-14.8, M-16.8, M-3 and M-20.8 are membranes with PEG content 14.8, 16.8, 18.8 and 20.8 wt %.
Mentions: The PVDF hollow fiber membranes SEM morphologies with different PEG content are shown in Figure 4. There was typical asymmetric structure in different PVDF membranes. The structure was made of a skin layer; an intermediate layer with finger-like structure; and a bottom layer with fully developed macrospores [22]. Finger-like structure dominates the cross section in M-14.8 and M-16.8 membranes. The sponge-structure in M-3 membrane becomes more and more obvious when compared to other membranes that have more finger-like structure. There are some defective structures in M-20.8 membrane. That can be explained by the solvent and non-solvent diffusion rate.

Bottom Line: The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence.The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea.The clearance rate of LZM was 66.8% and urea was 87.7%.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, China. haiyang19802005@163.com.

ABSTRACT
In this study, the separation properties of Polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were improved by optimizing membrane morphology and structure. The results showed that the PVDF membrane had better mechanical and separation properties than Fresenius Polysulfone High-Flux (F60S) membrane. The PVDF membrane tensile stress at break, tensile elongation and bursting pressure were 11.3 MPa, 395% and 0.625 MPa, respectively. Ultrafiltration (UF) flux of pure water reached 108.2 L∙h-1∙m-2 and rejection of Albumin from bovine serum was 82.3%. The PVDF dialyzers were prepared by centrifugal casting. The influences of membrane area and simulate fluid flow rate on dialysis performance were investigated. The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence. The high-flux PVDF dialyzer UF coefficient reached 62.6 mL/h/mmHg. The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea. The clearance rate of LZM was 66.8% and urea was 87.7%.

No MeSH data available.


Related in: MedlinePlus