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Preparation and preliminary dialysis performance research of polyvinylidene fluoride hollow fiber membranes.

Zhang Q, Lu X, Liu J, Zhao L - Membranes (Basel) (2015)

Bottom Line: The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence.The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea.The clearance rate of LZM was 66.8% and urea was 87.7%.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, China. haiyang19802005@163.com.

ABSTRACT
In this study, the separation properties of Polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were improved by optimizing membrane morphology and structure. The results showed that the PVDF membrane had better mechanical and separation properties than Fresenius Polysulfone High-Flux (F60S) membrane. The PVDF membrane tensile stress at break, tensile elongation and bursting pressure were 11.3 MPa, 395% and 0.625 MPa, respectively. Ultrafiltration (UF) flux of pure water reached 108.2 L∙h-1∙m-2 and rejection of Albumin from bovine serum was 82.3%. The PVDF dialyzers were prepared by centrifugal casting. The influences of membrane area and simulate fluid flow rate on dialysis performance were investigated. The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence. The high-flux PVDF dialyzer UF coefficient reached 62.6 mL/h/mmHg. The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea. The clearance rate of LZM was 66.8% and urea was 87.7%.

No MeSH data available.


Related in: MedlinePlus

The max pore size of PVDF membranes with different PEG molecular weight
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membranes-05-00120-f003: The max pore size of PVDF membranes with different PEG molecular weight

Mentions: From SEM morphologies of different PVDF membranes, it can be seen that the outer surface of the M-3 membrane is much denser, and the max pore size cannot be observed clearly while the outer surface of other membranes is rough and porous. The formation of pores becomes suppressed and smaller in the M-3 membrane. The diminishing of finger-like pores can increase the separation properties of PVDF membranes [21]. The max pore size of different membranes is shown in Figure 3.


Preparation and preliminary dialysis performance research of polyvinylidene fluoride hollow fiber membranes.

Zhang Q, Lu X, Liu J, Zhao L - Membranes (Basel) (2015)

The max pore size of PVDF membranes with different PEG molecular weight
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4384094&req=5

membranes-05-00120-f003: The max pore size of PVDF membranes with different PEG molecular weight
Mentions: From SEM morphologies of different PVDF membranes, it can be seen that the outer surface of the M-3 membrane is much denser, and the max pore size cannot be observed clearly while the outer surface of other membranes is rough and porous. The formation of pores becomes suppressed and smaller in the M-3 membrane. The diminishing of finger-like pores can increase the separation properties of PVDF membranes [21]. The max pore size of different membranes is shown in Figure 3.

Bottom Line: The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence.The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea.The clearance rate of LZM was 66.8% and urea was 87.7%.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, China. haiyang19802005@163.com.

ABSTRACT
In this study, the separation properties of Polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were improved by optimizing membrane morphology and structure. The results showed that the PVDF membrane had better mechanical and separation properties than Fresenius Polysulfone High-Flux (F60S) membrane. The PVDF membrane tensile stress at break, tensile elongation and bursting pressure were 11.3 MPa, 395% and 0.625 MPa, respectively. Ultrafiltration (UF) flux of pure water reached 108.2 L∙h-1∙m-2 and rejection of Albumin from bovine serum was 82.3%. The PVDF dialyzers were prepared by centrifugal casting. The influences of membrane area and simulate fluid flow rate on dialysis performance were investigated. The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence. The high-flux PVDF dialyzer UF coefficient reached 62.6 mL/h/mmHg. The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea. The clearance rate of LZM was 66.8% and urea was 87.7%.

No MeSH data available.


Related in: MedlinePlus