lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs.
Bottom Line: Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a comprehensive, manually curated reference database of 287 eukaryotic lncRNAs that have been described independently in the scientific literature.In addition to capturing a great proportion of the recent literature describing functions for individual lncRNAs, lncRNAdb now offers an improved user interface enabling greater accessibility to sequence information, expression data and the literature.The new features in lncRNAdb include the integration of Illumina Body Atlas expression profiles, nucleotide sequence information, a BLAST search tool and easy export of content via direct download or a REST API. lncRNAdb is now endorsed by RNAcentral and is in compliance with the International Nucleotide Sequence Database Collaboration.
Affiliation: Garvan Institute of Medical Research, 384 Victoria Street, Sydney, NSW 2010, Australia St Vincent's Clinical School, University of New South Wales, Sydney, NSW 2052, Australia.Show MeSH
Related in: MedlinePlus
Mentions: A new user interface with expanded features has been included to promote easily searchable and downloadable content, queried through lncRNA name, tissue or disease association (Figure 2). Entry pages are presented in an accordion-style format that allows users to expand or collapse various sections of the content. All records are available for download either as a useful printer-friendly summary or as an XML record for easy programmatic access.
Affiliation: Garvan Institute of Medical Research, 384 Victoria Street, Sydney, NSW 2010, Australia St Vincent's Clinical School, University of New South Wales, Sydney, NSW 2052, Australia.