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The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease.

Eppig JT, Blake JA, Bult CJ, Kadin JA, Richardson JE, Mouse Genome Database Gro - Nucleic Acids Res. (2014)

Bottom Line: MGD maintains a unified catalog of genes and genome features, including functional RNAs, QTL and phenotypic loci.MGD has also updated search paradigms for phenotypic allele attributes, incorporated incidental mutation data, added a module for display and exploration of genes and microRNA interactions and adopted the JBrowse genome browser.MGD resources are freely available to the scientific community.

View Article: PubMed Central - PubMed

Affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA janan.eppig@jax.org.

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Incidental Mutations from ENU experiments. Incidental mutations are accessed from the Gene Detail Page or Allele Detail Page. The top panel shows the Spag9 gene page with a link to two incidental mutations in this gene from the Mutagenetix mutation collection. Spag9 mutations were discovered in two mutant stocks from this collection. The bottom panel shows the Spag9m1Btlr allele detail page. Six incidental mutations were detected in the stock carrying this mutation.
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Figure 6: Incidental Mutations from ENU experiments. Incidental mutations are accessed from the Gene Detail Page or Allele Detail Page. The top panel shows the Spag9 gene page with a link to two incidental mutations in this gene from the Mutagenetix mutation collection. Spag9 mutations were discovered in two mutant stocks from this collection. The bottom panel shows the Spag9m1Btlr allele detail page. Six incidental mutations were detected in the stock carrying this mutation.

Mentions: To date, MGD provides incidental mutation data from the Mutagenetix project (19) and the Australian Phenomics Facility (20). We are currently working to import data from the Cardiovascular Development Consortium mutagenesis program (21), and additional sets of incidental mutation data will follow. Links to these data are found on MGD's Gene Detail Pages in the Mutations, Alleles and Phenotype ribbon and for incidental mutations occurring in a particular ENU mutation stock, links are provided on the Mutant Allele Detail Pages in the Mutation Details section (FigureĀ 6).


The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease.

Eppig JT, Blake JA, Bult CJ, Kadin JA, Richardson JE, Mouse Genome Database Gro - Nucleic Acids Res. (2014)

Incidental Mutations from ENU experiments. Incidental mutations are accessed from the Gene Detail Page or Allele Detail Page. The top panel shows the Spag9 gene page with a link to two incidental mutations in this gene from the Mutagenetix mutation collection. Spag9 mutations were discovered in two mutant stocks from this collection. The bottom panel shows the Spag9m1Btlr allele detail page. Six incidental mutations were detected in the stock carrying this mutation.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4384027&req=5

Figure 6: Incidental Mutations from ENU experiments. Incidental mutations are accessed from the Gene Detail Page or Allele Detail Page. The top panel shows the Spag9 gene page with a link to two incidental mutations in this gene from the Mutagenetix mutation collection. Spag9 mutations were discovered in two mutant stocks from this collection. The bottom panel shows the Spag9m1Btlr allele detail page. Six incidental mutations were detected in the stock carrying this mutation.
Mentions: To date, MGD provides incidental mutation data from the Mutagenetix project (19) and the Australian Phenomics Facility (20). We are currently working to import data from the Cardiovascular Development Consortium mutagenesis program (21), and additional sets of incidental mutation data will follow. Links to these data are found on MGD's Gene Detail Pages in the Mutations, Alleles and Phenotype ribbon and for incidental mutations occurring in a particular ENU mutation stock, links are provided on the Mutant Allele Detail Pages in the Mutation Details section (FigureĀ 6).

Bottom Line: MGD maintains a unified catalog of genes and genome features, including functional RNAs, QTL and phenotypic loci.MGD has also updated search paradigms for phenotypic allele attributes, incorporated incidental mutation data, added a module for display and exploration of genes and microRNA interactions and adopted the JBrowse genome browser.MGD resources are freely available to the scientific community.

View Article: PubMed Central - PubMed

Affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA janan.eppig@jax.org.

Show MeSH