CATH: comprehensive structural and functional annotations for genome sequences.
Bottom Line: The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235,000 protein domain structures and includes 25 million domain predictions.This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our 'current' putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages.
Affiliation: Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK email@example.com.Show MeSH
Mentions: Users have informed us that our web pages are often used to help teach students about the universe of known protein structures. We now provide tools to help users to browse through the different types of structures in CATH quickly and easily (see Figure 4).
Affiliation: Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK firstname.lastname@example.org.