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ViRBase: a resource for virus-host ncRNA-associated interactions.

Li Y, Wang C, Miao Z, Bi X, Wu D, Jin N, Wang L, Wu H, Qian K, Li C, Zhang T, Zhang C, Yi Y, Lai H, Hu Y, Cheng L, Leung KS, Li X, Zhang F, Li K, Li X, Wang D - Nucleic Acids Res. (2014)

Bottom Line: Viruses can use diverse ncRNAs to manipulate both cellular and viral gene expression to establish a host environment conducive to the completion of the viral life cycle.Many host cellular ncRNAs can also directly or indirectly influence viral replication and even target virus genomes.Users can query, browse and manipulate these virus-host ncRNA-associated interactions.

View Article: PubMed Central - PubMed

Affiliation: College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China.

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Related in: MedlinePlus

The overview of the ViRBase database.
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Figure 1: The overview of the ViRBase database.

Mentions: All interaction information was obtained from articles published in the PubMed database before August 2014. In the current version, ViRBase documents 12 247 ncRNA-associated virus–virus, virus–host, host–virus and host–host interactions in viral infection (including 11 816 experimental interactions and 431 predicted interactions), involving 462 non-redundant ncRNAs and 4463 protein-coding genes from 61 viruses and 24 hosts. Each entry contains detailed information on a virus–host ncRNA-associated interaction, including virus name, host species, ncRNA symbol, target symbol, validation method, Pubmed ID and detailed description (Figure 1).


ViRBase: a resource for virus-host ncRNA-associated interactions.

Li Y, Wang C, Miao Z, Bi X, Wu D, Jin N, Wang L, Wu H, Qian K, Li C, Zhang T, Zhang C, Yi Y, Lai H, Hu Y, Cheng L, Leung KS, Li X, Zhang F, Li K, Li X, Wang D - Nucleic Acids Res. (2014)

The overview of the ViRBase database.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4384010&req=5

Figure 1: The overview of the ViRBase database.
Mentions: All interaction information was obtained from articles published in the PubMed database before August 2014. In the current version, ViRBase documents 12 247 ncRNA-associated virus–virus, virus–host, host–virus and host–host interactions in viral infection (including 11 816 experimental interactions and 431 predicted interactions), involving 462 non-redundant ncRNAs and 4463 protein-coding genes from 61 viruses and 24 hosts. Each entry contains detailed information on a virus–host ncRNA-associated interaction, including virus name, host species, ncRNA symbol, target symbol, validation method, Pubmed ID and detailed description (Figure 1).

Bottom Line: Viruses can use diverse ncRNAs to manipulate both cellular and viral gene expression to establish a host environment conducive to the completion of the viral life cycle.Many host cellular ncRNAs can also directly or indirectly influence viral replication and even target virus genomes.Users can query, browse and manipulate these virus-host ncRNA-associated interactions.

View Article: PubMed Central - PubMed

Affiliation: College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Peking University Health Science Center, Beijing, China.

Show MeSH
Related in: MedlinePlus