The RCSB Protein Data Bank: views of structural biology for basic and applied research and education.
Bottom Line: Herein, we describe recently introduced data annotations including integration with external biological resources, such as gene and drug databases, new visualization tools and improved support for the mobile web.We also describe access to data files, web services and open access software components to enable software developers to more effectively mine the PDB archive and related annotations.Our efforts are aimed at expanding the role of 3D structure in understanding biology and medicine.
Affiliation: RCSB Protein Data Bank, San Diego Supercomputer Center, University of California San Diego, La Jolla, CA 92093, USA firstname.lastname@example.org.Show MeSH
Mentions: For data visualization, so-called ‘tracks’ are used (Figure 5). Color-coding on the left side of the view indicates the provenance of a track, e.g. all information coming from UniProt (44) is in green, PDB information is in blue, etc. In some cases, we are dealing with manually curated information, such as SCOP domains (45). Alternatively, the annotation has been inferred indirectly, as for Pfam domains (46), or calculated, as for hydropathy scores (47) and propensity for protein disorder score based on JRONN (P. Troshin and G. J. Barton, unpublished), a Java implementation of RONN (48).
Affiliation: RCSB Protein Data Bank, San Diego Supercomputer Center, University of California San Diego, La Jolla, CA 92093, USA email@example.com.