The neXtProt knowledgebase on human proteins: current status.
Bottom Line: Focused solely on human proteins, neXtProt aims to provide a state of the art resource for the representation of human biology by capturing a wide range of data, precise annotations, fully traceable data provenance and a web interface which enables researchers to find and view information in a comprehensive manner.Since the introductory neXtProt publication, significant advances have been made on three main aspects: the representation of proteomics data, an extended representation of human variants and the development of an advanced search capability built around semantic technologies.These changes are presented in the current neXtProt update.
Affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1211 Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 1211 firstname.lastname@example.org.Show MeSH
Mentions: We have completely restructured the neXtProt data model and infrastructure. The objective of these changes was to allow neXtProt users to precisely extract information that they are interested in; to manage list of proteins (originating from the results of searches, or created by users); and build analysis tools on top of neXtProt. Figure 2 gives an overview of the new neXtProt architecture and the technologies used.
Affiliation: CALIPHO group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland, 1211 Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland, 1211 email@example.com.