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Beyond protein expression, MOPED goes multi-omics.

Montague E, Janko I, Stanberry L, Lee E, Choiniere J, Anderson N, Stewart E, Broomall W, Higdon R, Kolker N, Kolker E - Nucleic Acids Res. (2014)

Bottom Line: These records correspond to 670 unique combinations of experiment, condition, localization and tissue.Advanced searching enables querying for genes, proteins, experiments, pathways and keywords of interest.The system is enhanced with visualizations for comparing across different data types.

View Article: PubMed Central - PubMed

Affiliation: Bioinformatics and High-Throughput Analysis Laboratory, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, WA, USA 98101 High-Throughput Analysis Core, Seattle Children's Research Institute, Seattle, WA, USA 98101 CDO Analytics, Seattle Children's, Seattle, WA, USA 98101 Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, WA, USA 98101.

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Related in: MedlinePlus

Absolute expression chart for two prominent ‘Nature’ proteome studies, which highlights the absolute expression of protein P07148 in standard conditions across different tissues (28,29).
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Figure 1: Absolute expression chart for two prominent ‘Nature’ proteome studies, which highlights the absolute expression of protein P07148 in standard conditions across different tissues (28,29).

Mentions: MOPED is continually expanding by monitoring and downloading new experimental data from public repositories: PRIDE, PeptideAtlas, proteomeXchange, ProteomicsDB and GEO (19–21), (http://proteomecentral.proteomexchange.org, https://www.proteomicsdb.org/). Recent additions to MOPED include two prominent Human Proteome studies of protein absolute expression data on 30 tissues and cell lines from the Pandey group (28) and on 21 tissues, cell lines and fluids from the Kuster group (Figure 1) (29) (raw data download from ProteomeXchange, PXD000561 and PXD000865). Other recent data additions include absolute expression from deep proteome profiling of 11 cell lines (30) and proteomics analysis of the NCI-60 cell line panel (31). To provide a valuable resource for investigating cancer mechanisms, transcriptomics data from the NCI-60 cell line panel (32) are being incorporated along with the proteomics data.


Beyond protein expression, MOPED goes multi-omics.

Montague E, Janko I, Stanberry L, Lee E, Choiniere J, Anderson N, Stewart E, Broomall W, Higdon R, Kolker N, Kolker E - Nucleic Acids Res. (2014)

Absolute expression chart for two prominent ‘Nature’ proteome studies, which highlights the absolute expression of protein P07148 in standard conditions across different tissues (28,29).
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4383969&req=5

Figure 1: Absolute expression chart for two prominent ‘Nature’ proteome studies, which highlights the absolute expression of protein P07148 in standard conditions across different tissues (28,29).
Mentions: MOPED is continually expanding by monitoring and downloading new experimental data from public repositories: PRIDE, PeptideAtlas, proteomeXchange, ProteomicsDB and GEO (19–21), (http://proteomecentral.proteomexchange.org, https://www.proteomicsdb.org/). Recent additions to MOPED include two prominent Human Proteome studies of protein absolute expression data on 30 tissues and cell lines from the Pandey group (28) and on 21 tissues, cell lines and fluids from the Kuster group (Figure 1) (29) (raw data download from ProteomeXchange, PXD000561 and PXD000865). Other recent data additions include absolute expression from deep proteome profiling of 11 cell lines (30) and proteomics analysis of the NCI-60 cell line panel (31). To provide a valuable resource for investigating cancer mechanisms, transcriptomics data from the NCI-60 cell line panel (32) are being incorporated along with the proteomics data.

Bottom Line: These records correspond to 670 unique combinations of experiment, condition, localization and tissue.Advanced searching enables querying for genes, proteins, experiments, pathways and keywords of interest.The system is enhanced with visualizations for comparing across different data types.

View Article: PubMed Central - PubMed

Affiliation: Bioinformatics and High-Throughput Analysis Laboratory, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, WA, USA 98101 High-Throughput Analysis Core, Seattle Children's Research Institute, Seattle, WA, USA 98101 CDO Analytics, Seattle Children's, Seattle, WA, USA 98101 Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, WA, USA 98101.

Show MeSH
Related in: MedlinePlus