DDMGD: the database of text-mined associations between genes methylated in diseases from different species.
Bottom Line: DDMGD provides a user-friendly interface facilitating retrieval of these associations ranked according to confidence scores.Submission of new associations to DDMGD is provided.A comparison analysis of DDMGD with several other databases focused on genes methylated in diseases shows that DDMGD is comprehensive and includes most of the recent information on genes methylated in diseases.
Affiliation: Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering Division (CEMSE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.Show MeSH
Mentions: DDMGD provides basic statistics about genes, diseases, species and associations. Figure 2 shows partial output of query ‘RASSF1A, lung cancer, human’. For example, for each gene, DDMGD lists the number of diseases and species with which the gene is associated, as well as the number of sentences, PubMed abstracts and PubMed Central articles that include the gene. DDMGD provides bar graphs that show the frequency of the associations found and downloadable connectivity graphs. The table at the bottom of the page allows the user to select associations of their interest to get more information such as color-highlighted evidence sentences and confidence scores (Figure 3). If a sentence contains associations between several genes, diseases and/or species, each association is stored as a separate record as shown in Figure 3.
Affiliation: Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering Division (CEMSE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.