LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs.
Bottom Line: Unlike existing databases, lncRNAWiki features comprehensive integration of information on human lncRNAs obtained from multiple different resources and allows not only existing lncRNAs to be edited, updated and curated by different users but also the addition of newly identified lncRNAs by any user.It harnesses community collective knowledge in collecting, editing and annotating human lncRNAs and rewards community-curated efforts by providing explicit authorship based on quantified contributions.LncRNAWiki relies on the underling knowledge of scientific community for collective and collaborative curation of human lncRNAs and thus has the potential to serve as an up-to-date and comprehensive knowledgebase for human lncRNAs.
Affiliation: CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.Show MeSH
Mentions: The central entities of lncRNAWiki are human lncRNA transcripts. Thus, each transcript has a corresponding wiki page (Figure 3). Meanwhile, transcripts are grouped together by classification categories, as well as by genes. This information can be accessed at the homepage and at the bottom of the transcript page. Transcript-specific pages are generated based on transcript identifiers. The content of every transcript in lncRNAWiki is structured into two parts: ‘user-edit’ part and ‘Basic Information’ part. The ‘user-edit’ part allows users to add or delete annotations. On the contrary, the ‘Basic Information’ portion is organized as a table and will be regularly updated by the lncRNAWiki team based on the annotation information integrated from multiple different lncRNA-associated sources. The lncRNA information in lncRNAWiki was seeded from GENCODE, NONCODE and LNCipedia, yielding a comprehensive integration of 105 255 non-redundant lncRNA transcripts (Figure 1).
Affiliation: CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.