LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs.
Bottom Line: Unlike existing databases, lncRNAWiki features comprehensive integration of information on human lncRNAs obtained from multiple different resources and allows not only existing lncRNAs to be edited, updated and curated by different users but also the addition of newly identified lncRNAs by any user.It harnesses community collective knowledge in collecting, editing and annotating human lncRNAs and rewards community-curated efforts by providing explicit authorship based on quantified contributions.LncRNAWiki relies on the underling knowledge of scientific community for collective and collaborative curation of human lncRNAs and thus has the potential to serve as an up-to-date and comprehensive knowledgebase for human lncRNAs.
Affiliation: CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.Show MeSH
Mentions: Based on our previous study (7) and categories of Derrien et al. (35), we classified the 105 255 non-redundant lncRNA transcripts into seven groups according to their genomic location in respect to protein-coding genes, viz., Intergenic, Intronic (S), Intronic (AS), Overlapping (S), Overlapping (AS), Sense and Antisense (Figure 2). The difference between our classification and Derrien's (35) is that we classified lncRNAs that intersect protein-coding genes into Sense or Antisense by considering the whole transcript sequence instead of exonic region only.
Affiliation: CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China.