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YM500v2: a small RNA sequencing (smRNA-seq) database for human cancer miRNome research.

Cheng WC, Chung IF, Tsai CF, Huang TS, Chen CY, Wang SC, Chang TY, Sun HJ, Chao JY, Cheng CC, Wu CW, Wang HW - Nucleic Acids Res. (2014)

Bottom Line: We previously presented YM500, which is an integrated database for miRNA quantification, isomiR identification, arm switching discovery and novel miRNA prediction from 468 human smRNA-seq datasets.A new function 'Meta-analysis' is additionally provided for allowing users to identify real-time differentially expressed miRNAs and arm-switching events according to customer-defined sample groups and dozens of clinical criteria tidying up by proficient clinicians.Cancer miRNAs identified hold the potential for both basic research and biotech applications.

View Article: PubMed Central - PubMed

Affiliation: Research Center for Tumor Medical Science, China Medical University, Taichung 40402, Taiwan.

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Related in: MedlinePlus

Two new charts for isomiRs. Panel (A) shows the percentage of samples that expressed the isomiR in various tissues, and panel (B) indicates the mean expression of a specific isomiR.
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Figure 3: Two new charts for isomiRs. Panel (A) shows the percentage of samples that expressed the isomiR in various tissues, and panel (B) indicates the mean expression of a specific isomiR.

Mentions: Two statistical charts are added to the ‘IsomiR’ section to help researchers realize the expression profile of an isomiR across distinct tissues. miR-21-5p+CA, an isomiR of miR-21-5p adenylated by PAPD5 reported to lead the degradation of miR-21-5p (24), is used as an example (Figure 3). Figure 3A shows the percentage of samples that expressed this isomiR in various tissues, and Figure 3B indicates the mean expression of a specific isomiR.


YM500v2: a small RNA sequencing (smRNA-seq) database for human cancer miRNome research.

Cheng WC, Chung IF, Tsai CF, Huang TS, Chen CY, Wang SC, Chang TY, Sun HJ, Chao JY, Cheng CC, Wu CW, Wang HW - Nucleic Acids Res. (2014)

Two new charts for isomiRs. Panel (A) shows the percentage of samples that expressed the isomiR in various tissues, and panel (B) indicates the mean expression of a specific isomiR.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4383957&req=5

Figure 3: Two new charts for isomiRs. Panel (A) shows the percentage of samples that expressed the isomiR in various tissues, and panel (B) indicates the mean expression of a specific isomiR.
Mentions: Two statistical charts are added to the ‘IsomiR’ section to help researchers realize the expression profile of an isomiR across distinct tissues. miR-21-5p+CA, an isomiR of miR-21-5p adenylated by PAPD5 reported to lead the degradation of miR-21-5p (24), is used as an example (Figure 3). Figure 3A shows the percentage of samples that expressed this isomiR in various tissues, and Figure 3B indicates the mean expression of a specific isomiR.

Bottom Line: We previously presented YM500, which is an integrated database for miRNA quantification, isomiR identification, arm switching discovery and novel miRNA prediction from 468 human smRNA-seq datasets.A new function 'Meta-analysis' is additionally provided for allowing users to identify real-time differentially expressed miRNAs and arm-switching events according to customer-defined sample groups and dozens of clinical criteria tidying up by proficient clinicians.Cancer miRNAs identified hold the potential for both basic research and biotech applications.

View Article: PubMed Central - PubMed

Affiliation: Research Center for Tumor Medical Science, China Medical University, Taichung 40402, Taiwan.

Show MeSH
Related in: MedlinePlus