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MethHC: a database of DNA methylation and gene expression in human cancer.

Huang WY, Hsu SD, Huang HY, Sun YM, Chou CH, Weng SL, Huang HD - Nucleic Acids Res. (2014)

Bottom Line: Increasing numbers of DNA methylation and mRNA/microRNA expression profiles are being published in different public repositories.These data can help researchers to identify epigenetic patterns that are important for carcinogenesis.MethHC integrates data such as DNA methylation, mRNA expression, DNA methylation of microRNA gene and microRNA expression to identify correlations between DNA methylation and mRNA/microRNA expression from TCGA (The Cancer Genome Atlas), which includes 18 human cancers in more than 6000 samples, 6548 microarrays and 12 567 RNA sequencing data.

View Article: PubMed Central - PubMed

Affiliation: Department of Biological Science and Technology, National Chiao Tung University, Hsin-Chu 300, Taiwan Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsin-Chu 300, Taiwan.

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Data generation flow of MethHC.
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Figure 1: Data generation flow of MethHC.

Mentions: Figure 1 shows the data generation flow of the MethHC database, which comprises two parts: (i) integration of experimental data source and (ii) integration of annotated databases. A detailed description is provided below.


MethHC: a database of DNA methylation and gene expression in human cancer.

Huang WY, Hsu SD, Huang HY, Sun YM, Chou CH, Weng SL, Huang HD - Nucleic Acids Res. (2014)

Data generation flow of MethHC.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4383953&req=5

Figure 1: Data generation flow of MethHC.
Mentions: Figure 1 shows the data generation flow of the MethHC database, which comprises two parts: (i) integration of experimental data source and (ii) integration of annotated databases. A detailed description is provided below.

Bottom Line: Increasing numbers of DNA methylation and mRNA/microRNA expression profiles are being published in different public repositories.These data can help researchers to identify epigenetic patterns that are important for carcinogenesis.MethHC integrates data such as DNA methylation, mRNA expression, DNA methylation of microRNA gene and microRNA expression to identify correlations between DNA methylation and mRNA/microRNA expression from TCGA (The Cancer Genome Atlas), which includes 18 human cancers in more than 6000 samples, 6548 microarrays and 12 567 RNA sequencing data.

View Article: PubMed Central - PubMed

Affiliation: Department of Biological Science and Technology, National Chiao Tung University, Hsin-Chu 300, Taiwan Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsin-Chu 300, Taiwan.

Show MeSH
Related in: MedlinePlus