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Congenital malformation of the vaginal orifice, imperforate vagina, in the common marmoset (Callithrix jacchus).

Niimi K, Oguchi A, Nishio K, Okano Y, Takahashi E - J. Vet. Med. Sci. (2014)

Bottom Line: There was no uterine and vaginal aplasia or atresia in her grossly normal genital tract.The plasma progesterone concentration suggested that the ovarian cycle had ceased.However, this may not be related to a functional anomaly, but rather to suppressed ovulation resulting from subordination to cagemates considering the various stages of follicular development observed.

View Article: PubMed Central - PubMed

Affiliation: Support Unit for Animal Resources Development, Research Resources Center, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.

ABSTRACT
The following is a report on a congenital vaginal malformation, imperforate vagina, in the common marmoset (Callithrix jacchus). This anomaly was observed for the first time in an adult female in our research colony. There was no uterine and vaginal aplasia or atresia in her grossly normal genital tract. The plasma progesterone concentration suggested that the ovarian cycle had ceased. However, this may not be related to a functional anomaly, but rather to suppressed ovulation resulting from subordination to cagemates considering the various stages of follicular development observed.

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Female genital tract morphology. The genital tract with the vulvar surface skin (a) wasdissected after perfusion with saline followed by 4% paraformaldehyde under deepanesthesia. Aplasia or atresia of the uterus and vagina was not observed in 254F (b) andappeared grossly similar to those of 275F (c) and 318F (d), with the exception of theimperforate vagina. The vaginal orifice in 254F was closed (e), whereas those of 275F(f) and 318F (g) were open. Various follicular stages, including mature follicles, wereobserved in 254F (h), similar to 275F (i) and 318F (j). This suggests that 254F had thecapacity for normal follicular development. Serial sections of the entire ovary did notshow a CL in 254F or 275F, whereas a CL was observed in 318F (j). The CL was indicatedby an arrow. Bar: 5 mm (b–d), 1 mm (e–j).
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fig_002: Female genital tract morphology. The genital tract with the vulvar surface skin (a) wasdissected after perfusion with saline followed by 4% paraformaldehyde under deepanesthesia. Aplasia or atresia of the uterus and vagina was not observed in 254F (b) andappeared grossly similar to those of 275F (c) and 318F (d), with the exception of theimperforate vagina. The vaginal orifice in 254F was closed (e), whereas those of 275F(f) and 318F (g) were open. Various follicular stages, including mature follicles, wereobserved in 254F (h), similar to 275F (i) and 318F (j). This suggests that 254F had thecapacity for normal follicular development. Serial sections of the entire ovary did notshow a CL in 254F or 275F, whereas a CL was observed in 318F (j). The CL was indicatedby an arrow. Bar: 5 mm (b–d), 1 mm (e–j).

Mentions: The female genital tracts, including the external vulvar skin (Fig. 2aFig. 2.


Congenital malformation of the vaginal orifice, imperforate vagina, in the common marmoset (Callithrix jacchus).

Niimi K, Oguchi A, Nishio K, Okano Y, Takahashi E - J. Vet. Med. Sci. (2014)

Female genital tract morphology. The genital tract with the vulvar surface skin (a) wasdissected after perfusion with saline followed by 4% paraformaldehyde under deepanesthesia. Aplasia or atresia of the uterus and vagina was not observed in 254F (b) andappeared grossly similar to those of 275F (c) and 318F (d), with the exception of theimperforate vagina. The vaginal orifice in 254F was closed (e), whereas those of 275F(f) and 318F (g) were open. Various follicular stages, including mature follicles, wereobserved in 254F (h), similar to 275F (i) and 318F (j). This suggests that 254F had thecapacity for normal follicular development. Serial sections of the entire ovary did notshow a CL in 254F or 275F, whereas a CL was observed in 318F (j). The CL was indicatedby an arrow. Bar: 5 mm (b–d), 1 mm (e–j).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4383783&req=5

fig_002: Female genital tract morphology. The genital tract with the vulvar surface skin (a) wasdissected after perfusion with saline followed by 4% paraformaldehyde under deepanesthesia. Aplasia or atresia of the uterus and vagina was not observed in 254F (b) andappeared grossly similar to those of 275F (c) and 318F (d), with the exception of theimperforate vagina. The vaginal orifice in 254F was closed (e), whereas those of 275F(f) and 318F (g) were open. Various follicular stages, including mature follicles, wereobserved in 254F (h), similar to 275F (i) and 318F (j). This suggests that 254F had thecapacity for normal follicular development. Serial sections of the entire ovary did notshow a CL in 254F or 275F, whereas a CL was observed in 318F (j). The CL was indicatedby an arrow. Bar: 5 mm (b–d), 1 mm (e–j).
Mentions: The female genital tracts, including the external vulvar skin (Fig. 2aFig. 2.

Bottom Line: There was no uterine and vaginal aplasia or atresia in her grossly normal genital tract.The plasma progesterone concentration suggested that the ovarian cycle had ceased.However, this may not be related to a functional anomaly, but rather to suppressed ovulation resulting from subordination to cagemates considering the various stages of follicular development observed.

View Article: PubMed Central - PubMed

Affiliation: Support Unit for Animal Resources Development, Research Resources Center, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.

ABSTRACT
The following is a report on a congenital vaginal malformation, imperforate vagina, in the common marmoset (Callithrix jacchus). This anomaly was observed for the first time in an adult female in our research colony. There was no uterine and vaginal aplasia or atresia in her grossly normal genital tract. The plasma progesterone concentration suggested that the ovarian cycle had ceased. However, this may not be related to a functional anomaly, but rather to suppressed ovulation resulting from subordination to cagemates considering the various stages of follicular development observed.

Show MeSH
Related in: MedlinePlus