Limits...
Cardiopulmonary response to exercise in COPD and overweight patients: relationship between unloaded cycling and maximal oxygen uptake profiles.

Ba A, Brégeon F, Delliaux S, Cissé F, Samb A, Jammes Y - Biomed Res Int (2015)

Bottom Line: Oxygen uptake (VO2), heart rate (HR), minute ventilation (VE), and respiratory frequency (fR) were averaged every 10 s.At the end of unloaded cycling period, HR increase was significantly accentuated in COPD and hypoxemic overweight subjects (resp., +14 ± 2 and +13 ± 1.5 min(-1), compared to +7.5 ± 1.5 min(-1) in normoxemic overweight subjects and +8 ± 1.8 min(-1) in controls).The plateau VE increase during unloaded cycling was positively correlated with VE values measured at the ventilatory threshold and VO2max.

View Article: PubMed Central - PubMed

Affiliation: Service des Explorations Fonctionnelles Respiratoires, Hopital Nord (Assistance Publique-Hôpitaux de Marseille) and UMR MD2, Faculté de Médecine Secteur Nord, Boulevard Pierre Dramard, 13916 Cedex 20 Marseille, France ; Laboratory of Physiology, Faculty of Medicine, University of Cheikh Anta Diop, Dakar, P.O. Box 45698, Dakar Fann, Dakar, Senegal ; Unité Mixte Internationale Environnement, Santé, Sociétés (UMI3189 ESS), Université Cheikh Anta Diop (UCAD), P.O. Box 5005, Dakar Fann, Senegal.

ABSTRACT
Cardiopulmonary response to unloaded cycling may be related to higher workloads. This was assessed in male subjects: 18 healthy sedentary subjects (controls), 14 hypoxemic patients with chronic obstructive pulmonary disease (COPD), and 31 overweight individuals (twelve were hypoxemic). They underwent an incremental exercise up to the maximal oxygen uptake (VO2max), preceded by a 2 min unloaded cycling period. Oxygen uptake (VO2), heart rate (HR), minute ventilation (VE), and respiratory frequency (fR) were averaged every 10 s. At the end of unloaded cycling period, HR increase was significantly accentuated in COPD and hypoxemic overweight subjects (resp., +14 ± 2 and +13 ± 1.5 min(-1), compared to +7.5 ± 1.5 min(-1) in normoxemic overweight subjects and +8 ± 1.8 min(-1) in controls). The fR increase was accentuated in all overweight subjects (hypoxemic: +4.5 ± 0.8; normoxemic: +3.9 ± 0.7 min(-1)) compared to controls (+2.5 ± 0.8 min(-1)) and COPDs (+2.0 ± 0.7 min(-1)). The plateau VE increase during unloaded cycling was positively correlated with VE values measured at the ventilatory threshold and VO2max. Measurement of ventilation during unloaded cycling may serve to predict the ventilatory performance of COPD patients and overweight subjects during an exercise rehabilitation program.

Show MeSH

Related in: MedlinePlus

Relationships between minute ventilation measured at the ventilatory threshold (VE threshold) and maximal oxygen uptake (VEmax) during an incremental cycling exercise and the maximal VE changes measured at 120 s of unloaded cycling exercise. All subjects were pooled together for this analysis. Regression line with 95% confidence intervals.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4383510&req=5

fig2: Relationships between minute ventilation measured at the ventilatory threshold (VE threshold) and maximal oxygen uptake (VEmax) during an incremental cycling exercise and the maximal VE changes measured at 120 s of unloaded cycling exercise. All subjects were pooled together for this analysis. Regression line with 95% confidence intervals.

Mentions: We found no relationship between HR changes measured at the end of unloaded cycling and HR values measured at determination of the ventilatory threshold and VO2max. By contrast, the plateau VE increase during unloaded cycling was positively correlated with the ventilation measured at the ventilatory threshold and VO2max (Figure 2). No correlation was found between the plateau increases in fR and VT during unloaded cycling and their corresponding changes at the ventilatory threshold and VO2max.


Cardiopulmonary response to exercise in COPD and overweight patients: relationship between unloaded cycling and maximal oxygen uptake profiles.

Ba A, Brégeon F, Delliaux S, Cissé F, Samb A, Jammes Y - Biomed Res Int (2015)

Relationships between minute ventilation measured at the ventilatory threshold (VE threshold) and maximal oxygen uptake (VEmax) during an incremental cycling exercise and the maximal VE changes measured at 120 s of unloaded cycling exercise. All subjects were pooled together for this analysis. Regression line with 95% confidence intervals.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4383510&req=5

fig2: Relationships between minute ventilation measured at the ventilatory threshold (VE threshold) and maximal oxygen uptake (VEmax) during an incremental cycling exercise and the maximal VE changes measured at 120 s of unloaded cycling exercise. All subjects were pooled together for this analysis. Regression line with 95% confidence intervals.
Mentions: We found no relationship between HR changes measured at the end of unloaded cycling and HR values measured at determination of the ventilatory threshold and VO2max. By contrast, the plateau VE increase during unloaded cycling was positively correlated with the ventilation measured at the ventilatory threshold and VO2max (Figure 2). No correlation was found between the plateau increases in fR and VT during unloaded cycling and their corresponding changes at the ventilatory threshold and VO2max.

Bottom Line: Oxygen uptake (VO2), heart rate (HR), minute ventilation (VE), and respiratory frequency (fR) were averaged every 10 s.At the end of unloaded cycling period, HR increase was significantly accentuated in COPD and hypoxemic overweight subjects (resp., +14 ± 2 and +13 ± 1.5 min(-1), compared to +7.5 ± 1.5 min(-1) in normoxemic overweight subjects and +8 ± 1.8 min(-1) in controls).The plateau VE increase during unloaded cycling was positively correlated with VE values measured at the ventilatory threshold and VO2max.

View Article: PubMed Central - PubMed

Affiliation: Service des Explorations Fonctionnelles Respiratoires, Hopital Nord (Assistance Publique-Hôpitaux de Marseille) and UMR MD2, Faculté de Médecine Secteur Nord, Boulevard Pierre Dramard, 13916 Cedex 20 Marseille, France ; Laboratory of Physiology, Faculty of Medicine, University of Cheikh Anta Diop, Dakar, P.O. Box 45698, Dakar Fann, Dakar, Senegal ; Unité Mixte Internationale Environnement, Santé, Sociétés (UMI3189 ESS), Université Cheikh Anta Diop (UCAD), P.O. Box 5005, Dakar Fann, Senegal.

ABSTRACT
Cardiopulmonary response to unloaded cycling may be related to higher workloads. This was assessed in male subjects: 18 healthy sedentary subjects (controls), 14 hypoxemic patients with chronic obstructive pulmonary disease (COPD), and 31 overweight individuals (twelve were hypoxemic). They underwent an incremental exercise up to the maximal oxygen uptake (VO2max), preceded by a 2 min unloaded cycling period. Oxygen uptake (VO2), heart rate (HR), minute ventilation (VE), and respiratory frequency (fR) were averaged every 10 s. At the end of unloaded cycling period, HR increase was significantly accentuated in COPD and hypoxemic overweight subjects (resp., +14 ± 2 and +13 ± 1.5 min(-1), compared to +7.5 ± 1.5 min(-1) in normoxemic overweight subjects and +8 ± 1.8 min(-1) in controls). The fR increase was accentuated in all overweight subjects (hypoxemic: +4.5 ± 0.8; normoxemic: +3.9 ± 0.7 min(-1)) compared to controls (+2.5 ± 0.8 min(-1)) and COPDs (+2.0 ± 0.7 min(-1)). The plateau VE increase during unloaded cycling was positively correlated with VE values measured at the ventilatory threshold and VO2max. Measurement of ventilation during unloaded cycling may serve to predict the ventilatory performance of COPD patients and overweight subjects during an exercise rehabilitation program.

Show MeSH
Related in: MedlinePlus