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PMMA third-body wear after unicondylar knee arthroplasty decuples the UHMWPE wear particle generation in vitro.

Paulus AC, Franke M, Kraxenberger M, Schröder C, Jansson V, Utzschneider S - Biomed Res Int (2015)

Bottom Line: The particles of all groups were similar in size and shape.The addition of bone or PMMA particles in terms of a third-body wear results in no change of particle size and morphology.PMMA third-bodies generated tenfold elevated particle numbers.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedic Surgery, University Hospital of Munich (LMU), Campus Großhadern, Marchioninistraße 15, 81377 Munich, Germany.

ABSTRACT

Introduction: Overlooked polymethylmethacrylate after unicondylar knee arthroplasty can be a potential problem, since this might influence the generated wear particle size and morphology. The aim of this study was the analysis of polyethylene wear in a knee wear simulator for changes in size, morphology, and particle number after the addition of third-bodies.

Material and methods: Fixed bearing unicondylar knee prostheses (UKA) were tested in a knee simulator for 5.0 million cycles. Following bone particles were added for 1.5 million cycles, followed by 1.5 million cycles with PMMA particles. A particle analysis by scanning electron microscopy of the lubricant after the cycles was performed. Size and morphology of the generated wear were characterized. Further, the number of particles per 1 million cycles was calculated for each group.

Results: The particles of all groups were similar in size and shape. The number of particles in the PMMA group showed 10-fold higher values than in the bone and control group (PMMA: 10.251 × 10(12); bone: 1.145 × 10(12); control: 1.804 × 10(12)).

Conclusion: The addition of bone or PMMA particles in terms of a third-body wear results in no change of particle size and morphology. PMMA third-bodies generated tenfold elevated particle numbers. This could favor an early aseptic loosening.

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Related in: MedlinePlus

The morphology of the particles given by the aspect ratio. The cement debris group tends towards more fibrillar particles. The results of all groups differ significantly (*P < 0.05).
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fig2: The morphology of the particles given by the aspect ratio. The cement debris group tends towards more fibrillar particles. The results of all groups differ significantly (*P < 0.05).

Mentions: Furthermore, the majority of all analyzed particles were approximately round in shape, smooth, granular, and irregular and had similar AR values (median): 1.34 (min: 1.00; max: 5.93) for the bone particle group, 1.51 (min: 1.00; max: 11.86) for the PMMA particle group, and 1.51 (min: 1.00; max: 9.90) for the control group. All size and shape parameters can be found in Table 2 (statistically significant results, P < 0.05). The particle size distribution is demonstrated in Figures 1 and 2 using box plots.


PMMA third-body wear after unicondylar knee arthroplasty decuples the UHMWPE wear particle generation in vitro.

Paulus AC, Franke M, Kraxenberger M, Schröder C, Jansson V, Utzschneider S - Biomed Res Int (2015)

The morphology of the particles given by the aspect ratio. The cement debris group tends towards more fibrillar particles. The results of all groups differ significantly (*P < 0.05).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4383432&req=5

fig2: The morphology of the particles given by the aspect ratio. The cement debris group tends towards more fibrillar particles. The results of all groups differ significantly (*P < 0.05).
Mentions: Furthermore, the majority of all analyzed particles were approximately round in shape, smooth, granular, and irregular and had similar AR values (median): 1.34 (min: 1.00; max: 5.93) for the bone particle group, 1.51 (min: 1.00; max: 11.86) for the PMMA particle group, and 1.51 (min: 1.00; max: 9.90) for the control group. All size and shape parameters can be found in Table 2 (statistically significant results, P < 0.05). The particle size distribution is demonstrated in Figures 1 and 2 using box plots.

Bottom Line: The particles of all groups were similar in size and shape.The addition of bone or PMMA particles in terms of a third-body wear results in no change of particle size and morphology.PMMA third-bodies generated tenfold elevated particle numbers.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedic Surgery, University Hospital of Munich (LMU), Campus Großhadern, Marchioninistraße 15, 81377 Munich, Germany.

ABSTRACT

Introduction: Overlooked polymethylmethacrylate after unicondylar knee arthroplasty can be a potential problem, since this might influence the generated wear particle size and morphology. The aim of this study was the analysis of polyethylene wear in a knee wear simulator for changes in size, morphology, and particle number after the addition of third-bodies.

Material and methods: Fixed bearing unicondylar knee prostheses (UKA) were tested in a knee simulator for 5.0 million cycles. Following bone particles were added for 1.5 million cycles, followed by 1.5 million cycles with PMMA particles. A particle analysis by scanning electron microscopy of the lubricant after the cycles was performed. Size and morphology of the generated wear were characterized. Further, the number of particles per 1 million cycles was calculated for each group.

Results: The particles of all groups were similar in size and shape. The number of particles in the PMMA group showed 10-fold higher values than in the bone and control group (PMMA: 10.251 × 10(12); bone: 1.145 × 10(12); control: 1.804 × 10(12)).

Conclusion: The addition of bone or PMMA particles in terms of a third-body wear results in no change of particle size and morphology. PMMA third-bodies generated tenfold elevated particle numbers. This could favor an early aseptic loosening.

Show MeSH
Related in: MedlinePlus