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Effects of verapamil SR and atenolol on 24-hour blood pressure and heart rate in hypertension patients with coronary artery disease: an international verapamil SR-trandolapril ambulatory monitoring substudy.

Denardo SJ, Gong Y, Cooper-DeHoff RM, Farsang C, Keltai M, Szirmai L, Messerli FH, Bavry AA, Handberg EM, Mancia G, Pepine CJ - PLoS ONE (2015)

Bottom Line: Clinicaltrials.gov; NCT00133692.

View Article: PubMed Central - PubMed

Affiliation: Division of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, Florida, United States of America.

ABSTRACT

Trial registration: Clinicaltrials.gov; NCT00133692.

No MeSH data available.


Office-based and 24-hour ambulatory monitoring systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) at baseline and following 1 year of treatment.The baseline data contain both verapamil SR- and atenolol-based strategies combined, while the data following 1 year of treatment is individualized to treatment strategy. For comparison, baseline office-based data for the remaining INVEST patients, who did not have ambulatory blood pressure monitoring, are shown to the left. Horizontal line through each box represents median; bottom and top of box represent first and third quartiles; the whiskers represent minimum and maximum of all data.
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pone.0122726.g002: Office-based and 24-hour ambulatory monitoring systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) at baseline and following 1 year of treatment.The baseline data contain both verapamil SR- and atenolol-based strategies combined, while the data following 1 year of treatment is individualized to treatment strategy. For comparison, baseline office-based data for the remaining INVEST patients, who did not have ambulatory blood pressure monitoring, are shown to the left. Horizontal line through each box represents median; bottom and top of box represent first and third quartiles; the whiskers represent minimum and maximum of all data.

Mentions: The 141 patients with ambulatory monitoring measurements were recruited from 13 sites, representing a 68% participation rate for this substudy. Technically valid BP and HR recordings were available in 117 patients both at baseline and after 1 year of treatment (Fig 1). Baseline clinical characteristics were similar for these 117 patients comparing treatment strategies (Table 1). Additionally, baseline office SBP, DBP, and HR were similar for these patients and were also similar to the remaining 22,459 INVEST patients (Fig 2).


Effects of verapamil SR and atenolol on 24-hour blood pressure and heart rate in hypertension patients with coronary artery disease: an international verapamil SR-trandolapril ambulatory monitoring substudy.

Denardo SJ, Gong Y, Cooper-DeHoff RM, Farsang C, Keltai M, Szirmai L, Messerli FH, Bavry AA, Handberg EM, Mancia G, Pepine CJ - PLoS ONE (2015)

Office-based and 24-hour ambulatory monitoring systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) at baseline and following 1 year of treatment.The baseline data contain both verapamil SR- and atenolol-based strategies combined, while the data following 1 year of treatment is individualized to treatment strategy. For comparison, baseline office-based data for the remaining INVEST patients, who did not have ambulatory blood pressure monitoring, are shown to the left. Horizontal line through each box represents median; bottom and top of box represent first and third quartiles; the whiskers represent minimum and maximum of all data.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4383326&req=5

pone.0122726.g002: Office-based and 24-hour ambulatory monitoring systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) at baseline and following 1 year of treatment.The baseline data contain both verapamil SR- and atenolol-based strategies combined, while the data following 1 year of treatment is individualized to treatment strategy. For comparison, baseline office-based data for the remaining INVEST patients, who did not have ambulatory blood pressure monitoring, are shown to the left. Horizontal line through each box represents median; bottom and top of box represent first and third quartiles; the whiskers represent minimum and maximum of all data.
Mentions: The 141 patients with ambulatory monitoring measurements were recruited from 13 sites, representing a 68% participation rate for this substudy. Technically valid BP and HR recordings were available in 117 patients both at baseline and after 1 year of treatment (Fig 1). Baseline clinical characteristics were similar for these 117 patients comparing treatment strategies (Table 1). Additionally, baseline office SBP, DBP, and HR were similar for these patients and were also similar to the remaining 22,459 INVEST patients (Fig 2).

Bottom Line: Clinicaltrials.gov; NCT00133692.

View Article: PubMed Central - PubMed

Affiliation: Division of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville, Florida, United States of America.

ABSTRACT

Trial registration: Clinicaltrials.gov; NCT00133692.

No MeSH data available.