Limits...
Clinical application of ultrasound-guided core needle biopsy with multiple punches in the diagnosis of lymphoma.

He Y, Ji X, Xie Y, He B, Xu X, Chen X, Zhang Q - World J Surg Oncol (2015)

Bottom Line: From March 2007 to October 2013, US-guided CNB with multiple punches was performed by well-experienced radiologists in 110 patients (CNB group), and surgical biopsy was carried out in 95 patients (surgical group).There were no statistical differences between the CNB group and the surgical group in the diagnostic accuracy rate of lymphoma, as well as its subtypes in superficial and deep masses.US-guided CNB with no less than three punches is an accurate, safe, minimally invasive, non-radiological, fast, and cost-effective method in the evaluation of lymphoma and its subtypes as compared with surgical approach.

View Article: PubMed Central - PubMed

Affiliation: Department of Ultrasound, The Cancer Hospital of Nantong University, No. 30 Tongyang North Road, Pingchao Town, Tongzhou District, Nantong, 226361, China. heying0520@163.com.

ABSTRACT

Background: The purpose of this study is to investigate the feasibility, accuracy, and limitations of ultrasound (US)-guided core needle biopsy (CNB) with multiple punches in the diagnosis of lymphoma in the whole body.

Methods: From March 2007 to October 2013, US-guided CNB with multiple punches was performed by well-experienced radiologists in 110 patients (CNB group), and surgical biopsy was carried out in 95 patients (surgical group). The differences of accuracy rate between the two groups in the diagnosis of lymphoma and its subtypes were examined with Fisher's exact test.

Results: There were no statistical differences between the CNB group and the surgical group in the diagnostic accuracy rate of lymphoma, as well as its subtypes in superficial and deep masses. In addition, in the CNB group, there were no statistical differences between different lengths of lesions in the diagnosis accuracy rate of lymphoma and its subtypes.

Conclusions: US-guided CNB with no less than three punches is an accurate, safe, minimally invasive, non-radiological, fast, and cost-effective method in the evaluation of lymphoma and its subtypes as compared with surgical approach. It should be considered as the acceptable alternative to surgical biopsy to obtain histopathological samples in the patients with suspected lymphoma.

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Related in: MedlinePlus

Bard Magnum tissue-cutting needle and the third generation automatic biopsy gun (big arrow); tissue strips obtained with CNB (small arrow).
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Fig1: Bard Magnum tissue-cutting needle and the third generation automatic biopsy gun (big arrow); tissue strips obtained with CNB (small arrow).

Mentions: All biopsies were conducted under the supervision of color doppler ultrasonography (Philips IU-22, Amsterdam, The Netherlands) with probe frequencies of 2 to 5 MHz (low frequency) and 5 to 12 MHz (high frequency). The 14-gauge (14G) and 16-gauge (16G) cutting needles and the third generation automatic biopsy gun (Bard Magnum, Covington, GA, USA) (Figure 1) were used to the biopsies. The length of needle groove was 15 or 22 mm, depending upon the size of nodal and proximity of vessels [18]. The high-frequency probe-guided 14G core needle and low-frequency probe-guided 16G core needle were used to the biopsies of superficial and deep masses, respectively (Figure 2).Figure 1


Clinical application of ultrasound-guided core needle biopsy with multiple punches in the diagnosis of lymphoma.

He Y, Ji X, Xie Y, He B, Xu X, Chen X, Zhang Q - World J Surg Oncol (2015)

Bard Magnum tissue-cutting needle and the third generation automatic biopsy gun (big arrow); tissue strips obtained with CNB (small arrow).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4383197&req=5

Fig1: Bard Magnum tissue-cutting needle and the third generation automatic biopsy gun (big arrow); tissue strips obtained with CNB (small arrow).
Mentions: All biopsies were conducted under the supervision of color doppler ultrasonography (Philips IU-22, Amsterdam, The Netherlands) with probe frequencies of 2 to 5 MHz (low frequency) and 5 to 12 MHz (high frequency). The 14-gauge (14G) and 16-gauge (16G) cutting needles and the third generation automatic biopsy gun (Bard Magnum, Covington, GA, USA) (Figure 1) were used to the biopsies. The length of needle groove was 15 or 22 mm, depending upon the size of nodal and proximity of vessels [18]. The high-frequency probe-guided 14G core needle and low-frequency probe-guided 16G core needle were used to the biopsies of superficial and deep masses, respectively (Figure 2).Figure 1

Bottom Line: From March 2007 to October 2013, US-guided CNB with multiple punches was performed by well-experienced radiologists in 110 patients (CNB group), and surgical biopsy was carried out in 95 patients (surgical group).There were no statistical differences between the CNB group and the surgical group in the diagnostic accuracy rate of lymphoma, as well as its subtypes in superficial and deep masses.US-guided CNB with no less than three punches is an accurate, safe, minimally invasive, non-radiological, fast, and cost-effective method in the evaluation of lymphoma and its subtypes as compared with surgical approach.

View Article: PubMed Central - PubMed

Affiliation: Department of Ultrasound, The Cancer Hospital of Nantong University, No. 30 Tongyang North Road, Pingchao Town, Tongzhou District, Nantong, 226361, China. heying0520@163.com.

ABSTRACT

Background: The purpose of this study is to investigate the feasibility, accuracy, and limitations of ultrasound (US)-guided core needle biopsy (CNB) with multiple punches in the diagnosis of lymphoma in the whole body.

Methods: From March 2007 to October 2013, US-guided CNB with multiple punches was performed by well-experienced radiologists in 110 patients (CNB group), and surgical biopsy was carried out in 95 patients (surgical group). The differences of accuracy rate between the two groups in the diagnosis of lymphoma and its subtypes were examined with Fisher's exact test.

Results: There were no statistical differences between the CNB group and the surgical group in the diagnostic accuracy rate of lymphoma, as well as its subtypes in superficial and deep masses. In addition, in the CNB group, there were no statistical differences between different lengths of lesions in the diagnosis accuracy rate of lymphoma and its subtypes.

Conclusions: US-guided CNB with no less than three punches is an accurate, safe, minimally invasive, non-radiological, fast, and cost-effective method in the evaluation of lymphoma and its subtypes as compared with surgical approach. It should be considered as the acceptable alternative to surgical biopsy to obtain histopathological samples in the patients with suspected lymphoma.

Show MeSH
Related in: MedlinePlus