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Increase in anaphylaxis-related hospitalizations but no increase in fatalities: an analysis of United Kingdom national anaphylaxis data, 1992-2012.

Turner PJ, Gowland MH, Sharma V, Ierodiakonou D, Harper N, Garcez T, Pumphrey R, Boyle RJ - J. Allergy Clin. Immunol. (2014)

Bottom Line: These findings are not explained by age-related differences in rates of hospitalization.This might be due to increasing awareness of the diagnosis, shifting patterns of behavior in patients and health care providers, or both.The age distribution of fatal anaphylaxis varies significantly according to the nature of the eliciting agent, which suggests a specific vulnerability to severe outcomes from food-induced allergic reactions in the second and third decades.

View Article: PubMed Central - PubMed

Affiliation: Section of Paediatrics (Allergy & Immunology) and MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom; Division of Paediatrics and Child Health, University of Sydney, Sydney, Australia. Electronic address: paulyt@doctors.org.uk.

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Prescription of epinephrine autoinjectors to English residents from 1998 to 2012.
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fig6: Prescription of epinephrine autoinjectors to English residents from 1998 to 2012.

Mentions: The prescription of epinephrine autoinjector devices to residents in England increased by 325% from 1998 to 2012 (P < .0001, Fig 6). The estimated rate ratio was 1.113 (95% CI, 1.112-1.113) over the study period.


Increase in anaphylaxis-related hospitalizations but no increase in fatalities: an analysis of United Kingdom national anaphylaxis data, 1992-2012.

Turner PJ, Gowland MH, Sharma V, Ierodiakonou D, Harper N, Garcez T, Pumphrey R, Boyle RJ - J. Allergy Clin. Immunol. (2014)

Prescription of epinephrine autoinjectors to English residents from 1998 to 2012.
© Copyright Policy - CC BY
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4382330&req=5

fig6: Prescription of epinephrine autoinjectors to English residents from 1998 to 2012.
Mentions: The prescription of epinephrine autoinjector devices to residents in England increased by 325% from 1998 to 2012 (P < .0001, Fig 6). The estimated rate ratio was 1.113 (95% CI, 1.112-1.113) over the study period.

Bottom Line: These findings are not explained by age-related differences in rates of hospitalization.This might be due to increasing awareness of the diagnosis, shifting patterns of behavior in patients and health care providers, or both.The age distribution of fatal anaphylaxis varies significantly according to the nature of the eliciting agent, which suggests a specific vulnerability to severe outcomes from food-induced allergic reactions in the second and third decades.

View Article: PubMed Central - PubMed

Affiliation: Section of Paediatrics (Allergy & Immunology) and MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom; Division of Paediatrics and Child Health, University of Sydney, Sydney, Australia. Electronic address: paulyt@doctors.org.uk.

Show MeSH
Related in: MedlinePlus