Ebola: a holistic approach is required to achieve effective management and control.
Bottom Line: The scale of the epidemic has accelerated research efforts for diagnostics, treatment, and prevention galvanized through increased availability of funding.However, there is a long way to go.In this review we summarize the current knowledge, examine the sociocultural context in West Africa, and outline priority areas for future research.
Affiliation: The Medical Research Unit (MRC), Fajara, The Gambia.Show MeSH
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Mentions: The process of replication and transcription of the viral genome is activated by the VPs that contain the nucleoprotein.24,25 When compared with Marburg virus, the N-terminal region of nucleoprotein defines the inner diameter of the EV nucleocapside, whereas the RNA genome defines its length.26 The details of viral assembly are summarized in Fig 2.
Affiliation: The Medical Research Unit (MRC), Fajara, The Gambia.