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Yields and Utility of Endoscopic Ultrasonography-Guided 19-Gauge Trucut Biopsy versus 22-Gauge Fine Needle Aspiration for Diagnosing Gastric Subepithelial Tumors.

Na HK, Lee JH, Park YS, Ahn JY, Choi KS, Kim do H, Choi KD, Song HJ, Lee GH, Jung HY, Kim JH - Clin Endosc (2015)

Bottom Line: There were nine technical failures with TCB, and the rate of adverse events did not differ between the groups (TCB vs.FNA, 3.3% vs. 8.1%; p=0.27).Nineteen-gauge TCB is safe and highly valuable for diagnosing gastric SETs larger than 2 cm if technical failure can be avoided.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

ABSTRACT

Background/aims: To evaluate the yields and utility of 19-gauge (G) Trucut biopsy (TCB) versus 22 G fine needle aspiration (FNA) for diagnosing gastric subepithelial tumors (SETs).

Methods: We retrieved data for 152 patients with a gastric SET larger than 2 cm who had undergone endoscopic ultrasonography (EUS)-guided 19 G TCB (n=90) or 22 G FNA (n=62). Relevant clinical, tumor-specific, and EUS procedural information was reviewed retrospectively.

Results: A specific diagnosis was made for 76 gastrointestinal stromal tumors (GISTs) and 51 non-GIST SETs. The diagnostic yield of TCB was greater than that of FNA (77.8% vs. 38.7%, p<0.001). The percentage of non-diagnostic specimens (suspicious and insufficient) was significantly lower in the TCB group (6.7% and 15.5%, respectively) than in the FNA group (22.6% and 38.7%, respectively; both p<0.001). TCB accurately diagnosed 90.9% of GISTs and 81.1% of non-GIST SETs, whereas FNA accurately diagnosed 68.8% of GISTs and 14.3% of non-GIST SETs. There were nine technical failures with TCB, and the rate of adverse events did not differ between the groups (TCB vs. FNA, 3.3% vs. 8.1%; p=0.27).

Conclusions: Nineteen-gauge TCB is safe and highly valuable for diagnosing gastric SETs larger than 2 cm if technical failure can be avoided.

No MeSH data available.


Related in: MedlinePlus

Diagnostic yields of 22-gauge (G) fine needle aspiration (FNA) and 19 G Trucut biopsy (TCB).
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Figure 2: Diagnostic yields of 22-gauge (G) fine needle aspiration (FNA) and 19 G Trucut biopsy (TCB).

Mentions: The overall diagnostic yield of EUS-guided needle sampling was 61.8% (Fig. 2). The diagnostic yield of 19 G TCB was significantly higher than that of 22 G FNA (77.8% vs. 38.7%, p<0.001). The percentages of nondiagnostic specimens (suspicious and insufficient) were significantly lower for TCB (6.7% and 15.5%, respectively) than for FNA (22.6% and 38.7%, respectively). Of 76 GISTs, diagnostic specimens were obtained for 90.9% of tumors using TCB and 68.8% of tumors using FNA (p=0.02) (Fig. 3). Of 51 non-GIST SETs, the diagnostic yields were 81.1% using TCB and 14.3% using FNA (p<0.001).


Yields and Utility of Endoscopic Ultrasonography-Guided 19-Gauge Trucut Biopsy versus 22-Gauge Fine Needle Aspiration for Diagnosing Gastric Subepithelial Tumors.

Na HK, Lee JH, Park YS, Ahn JY, Choi KS, Kim do H, Choi KD, Song HJ, Lee GH, Jung HY, Kim JH - Clin Endosc (2015)

Diagnostic yields of 22-gauge (G) fine needle aspiration (FNA) and 19 G Trucut biopsy (TCB).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4381143&req=5

Figure 2: Diagnostic yields of 22-gauge (G) fine needle aspiration (FNA) and 19 G Trucut biopsy (TCB).
Mentions: The overall diagnostic yield of EUS-guided needle sampling was 61.8% (Fig. 2). The diagnostic yield of 19 G TCB was significantly higher than that of 22 G FNA (77.8% vs. 38.7%, p<0.001). The percentages of nondiagnostic specimens (suspicious and insufficient) were significantly lower for TCB (6.7% and 15.5%, respectively) than for FNA (22.6% and 38.7%, respectively). Of 76 GISTs, diagnostic specimens were obtained for 90.9% of tumors using TCB and 68.8% of tumors using FNA (p=0.02) (Fig. 3). Of 51 non-GIST SETs, the diagnostic yields were 81.1% using TCB and 14.3% using FNA (p<0.001).

Bottom Line: There were nine technical failures with TCB, and the rate of adverse events did not differ between the groups (TCB vs.FNA, 3.3% vs. 8.1%; p=0.27).Nineteen-gauge TCB is safe and highly valuable for diagnosing gastric SETs larger than 2 cm if technical failure can be avoided.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

ABSTRACT

Background/aims: To evaluate the yields and utility of 19-gauge (G) Trucut biopsy (TCB) versus 22 G fine needle aspiration (FNA) for diagnosing gastric subepithelial tumors (SETs).

Methods: We retrieved data for 152 patients with a gastric SET larger than 2 cm who had undergone endoscopic ultrasonography (EUS)-guided 19 G TCB (n=90) or 22 G FNA (n=62). Relevant clinical, tumor-specific, and EUS procedural information was reviewed retrospectively.

Results: A specific diagnosis was made for 76 gastrointestinal stromal tumors (GISTs) and 51 non-GIST SETs. The diagnostic yield of TCB was greater than that of FNA (77.8% vs. 38.7%, p<0.001). The percentage of non-diagnostic specimens (suspicious and insufficient) was significantly lower in the TCB group (6.7% and 15.5%, respectively) than in the FNA group (22.6% and 38.7%, respectively; both p<0.001). TCB accurately diagnosed 90.9% of GISTs and 81.1% of non-GIST SETs, whereas FNA accurately diagnosed 68.8% of GISTs and 14.3% of non-GIST SETs. There were nine technical failures with TCB, and the rate of adverse events did not differ between the groups (TCB vs. FNA, 3.3% vs. 8.1%; p=0.27).

Conclusions: Nineteen-gauge TCB is safe and highly valuable for diagnosing gastric SETs larger than 2 cm if technical failure can be avoided.

No MeSH data available.


Related in: MedlinePlus