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CHOPIN: a web resource for the structural and functional proteome of Mycobacterium tuberculosis.

Ochoa-Montaño B, Mohan N, Blundell TL - Database (Oxford) (2015)

Bottom Line: Additionally, CHOPIN includes structural analyses of mutations potentially associated with drug resistance.Results are made available at the web interface, which also serves as an automatically updated repository of all published Mtb experimental structures.Its RESTful interface allows direct and flexible access to structures and metadata via intuitive URLs, enabling easy programmatic use of the models.

View Article: PubMed Central - PubMed

Affiliation: Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, UK and Department of Biotechnology, Indian Institute of Technology Madras, Chennai, Tamil Nadu 600036, India bernardo@cryst.bioc.cam.ac.uk.

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Overview of the CHOPIN modelling pipeline.
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bav026-F1: Overview of the CHOPIN modelling pipeline.

Mentions: An overview of the modelling pipeline is illustrated on Fig. 1. It begins with the set of FASTA-formatted sequences from the H37Rv reference genome, as obtained from the Tuberculosis Database (TBDB) website (16) and outputs a set of models and alignments, together with a relational database of the data necessary for the web interface.Figure 1.


CHOPIN: a web resource for the structural and functional proteome of Mycobacterium tuberculosis.

Ochoa-Montaño B, Mohan N, Blundell TL - Database (Oxford) (2015)

Overview of the CHOPIN modelling pipeline.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4381106&req=5

bav026-F1: Overview of the CHOPIN modelling pipeline.
Mentions: An overview of the modelling pipeline is illustrated on Fig. 1. It begins with the set of FASTA-formatted sequences from the H37Rv reference genome, as obtained from the Tuberculosis Database (TBDB) website (16) and outputs a set of models and alignments, together with a relational database of the data necessary for the web interface.Figure 1.

Bottom Line: Additionally, CHOPIN includes structural analyses of mutations potentially associated with drug resistance.Results are made available at the web interface, which also serves as an automatically updated repository of all published Mtb experimental structures.Its RESTful interface allows direct and flexible access to structures and metadata via intuitive URLs, enabling easy programmatic use of the models.

View Article: PubMed Central - PubMed

Affiliation: Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, UK and Department of Biotechnology, Indian Institute of Technology Madras, Chennai, Tamil Nadu 600036, India bernardo@cryst.bioc.cam.ac.uk.

Show MeSH
Related in: MedlinePlus