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Hair Regeneration Treatment Using Adipose-Derived Stem Cell Conditioned Medium: Follow-up With Trichograms.

Fukuoka H, Suga H - Eplasty (2015)

Bottom Line: Hair numbers were significantly increased after treatment in both male (including those without finasteride administration) and female patients.In the half-side comparison study, the increase in hair numbers was significantly higher on the treatment side than on the placebo side.Treatment using adipose-derived stem cell-conditioned medium appears highly effective for alopecia and may represent a new therapy for hair regeneration.

View Article: PubMed Central - PubMed

Affiliation: Cherry-Blossom Plastic and Regenerative Surgery, Tokyo, Japan; and Department of Plastic and Reconstructive Surgery, Kyorin University, Tokyo, Japan.

ABSTRACT

Objective: Adipose-derived stem cells secrete various growth factors that promote hair growth. This study examined the effects of adipose-derived stem cell-conditioned medium on alopecia.

Methods: Adipose-derived stem cell-conditioned medium was intradermally injected in 22 patients (11 men and 11 women) with alopecia. Patients received treatment every 3 to 5 weeks for a total of 6 sessions. Hair numbers were counted using trichograms before and after treatment. A half-side comparison study was also performed in 10 patients (8 men and 2 women).

Results: Hair numbers were significantly increased after treatment in both male (including those without finasteride administration) and female patients. In the half-side comparison study, the increase in hair numbers was significantly higher on the treatment side than on the placebo side.

Conclusion: Treatment using adipose-derived stem cell-conditioned medium appears highly effective for alopecia and may represent a new therapy for hair regeneration.

No MeSH data available.


Increases in the number of hairs in the half-side comparison study. *P < .01.
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Figure 7: Increases in the number of hairs in the half-side comparison study. *P < .01.

Mentions: In the half-side comparison study, the number of hairs was significantly increased after treatment on both the left (adipose-derived stem cell-conditioned medium) and right (placebo) sides (Fig 6). However, the increase in the number of hairs was significantly higher on the left (adipose-derived stem cell-conditioned medium) side than on the right (placebo) side (Fig 7).


Hair Regeneration Treatment Using Adipose-Derived Stem Cell Conditioned Medium: Follow-up With Trichograms.

Fukuoka H, Suga H - Eplasty (2015)

Increases in the number of hairs in the half-side comparison study. *P < .01.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4379938&req=5

Figure 7: Increases in the number of hairs in the half-side comparison study. *P < .01.
Mentions: In the half-side comparison study, the number of hairs was significantly increased after treatment on both the left (adipose-derived stem cell-conditioned medium) and right (placebo) sides (Fig 6). However, the increase in the number of hairs was significantly higher on the left (adipose-derived stem cell-conditioned medium) side than on the right (placebo) side (Fig 7).

Bottom Line: Hair numbers were significantly increased after treatment in both male (including those without finasteride administration) and female patients.In the half-side comparison study, the increase in hair numbers was significantly higher on the treatment side than on the placebo side.Treatment using adipose-derived stem cell-conditioned medium appears highly effective for alopecia and may represent a new therapy for hair regeneration.

View Article: PubMed Central - PubMed

Affiliation: Cherry-Blossom Plastic and Regenerative Surgery, Tokyo, Japan; and Department of Plastic and Reconstructive Surgery, Kyorin University, Tokyo, Japan.

ABSTRACT

Objective: Adipose-derived stem cells secrete various growth factors that promote hair growth. This study examined the effects of adipose-derived stem cell-conditioned medium on alopecia.

Methods: Adipose-derived stem cell-conditioned medium was intradermally injected in 22 patients (11 men and 11 women) with alopecia. Patients received treatment every 3 to 5 weeks for a total of 6 sessions. Hair numbers were counted using trichograms before and after treatment. A half-side comparison study was also performed in 10 patients (8 men and 2 women).

Results: Hair numbers were significantly increased after treatment in both male (including those without finasteride administration) and female patients. In the half-side comparison study, the increase in hair numbers was significantly higher on the treatment side than on the placebo side.

Conclusion: Treatment using adipose-derived stem cell-conditioned medium appears highly effective for alopecia and may represent a new therapy for hair regeneration.

No MeSH data available.