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Effects of a food-based intervention on markers of micronutrient status among Indian women of low socio-economic status.

Kehoe SH, Chopra H, Sahariah SA, Bhat D, Munshi RP, Panchal F, Young S, Brown N, Tarwande D, Gandhi M, Margetts BM, Potdar RD, Fall CH - Br. J. Nutr. (2015)

Bottom Line: We assessed the effects of group allocation on 12-week nutrient concentrations using ANCOVA models with respective 0-week concentrations, BMI, compliance, standard of living, fruit and green leafy vegetable consumption and use of synthetic nutrients as covariates.The treatment snack significantly increased β-carotene concentrations (treatment effect: 47·1 nmol/l, 95 % CI 6·5, 87·7).There was no effect of group allocation on concentrations of ferritin, retinol, ascorbate, folate or vitamin B12.

View Article: PubMed Central - PubMed

Affiliation: Medical Research Council Lifecourse Epidemiology Unit, University of Southampton,Southampton,UK.

ABSTRACT
Intakes of micronutrient-rich foods are low among Indian women of reproductive age. We investigated whether consumption of a food-based micronutrient-rich snack increased markers of blood micronutrient concentrations when compared with a control snack. Non-pregnant women (n 222) aged 14-35 years living in a Mumbai slum were randomised to receive a treatment snack (containing green leafy vegetables, dried fruit and whole milk powder), or a control snack containing foods of low micronutrient content such as wheat flour, potato and tapioca. The snacks were consumed under observation 6 d per week for 12 weeks, compliance was recorded, and blood was collected at 0 and 12 weeks. Food-frequency data were collected at both time points. Compliance (defined as the proportion of women who consumed ≥ 3 snacks/week) was >85 % in both groups. We assessed the effects of group allocation on 12-week nutrient concentrations using ANCOVA models with respective 0-week concentrations, BMI, compliance, standard of living, fruit and green leafy vegetable consumption and use of synthetic nutrients as covariates. The treatment snack significantly increased β-carotene concentrations (treatment effect: 47·1 nmol/l, 95 % CI 6·5, 87·7). There was no effect of group allocation on concentrations of ferritin, retinol, ascorbate, folate or vitamin B12. The present study shows that locally sourced foods can be made into acceptable snacks that may increase serum β-carotene concentrations among women of reproductive age. However, no increase in circulating concentrations of the other nutrients measured was observed.

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Flow chart of the study participants.
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fig1: Flow chart of the study participants.

Mentions: Of the 222 women randomised, a total of 208 women with baseline blood measurements started receiving the intervention (Fig. 1). Of these, blood was collected at 12 weeks from 172 women and blood samples were available at both time points for 170 women. Compliance (defined as the proportion of women who consumed ≥ 3 snacks per week) was 85 % in the treatment and 90 % in the control groups. The median weekly snack consumption of those in the final analysis was 5·0 (IQR 4·4–5·5) in the control group and 4·9 (IQR 3·8–5·3) in the treatment group.Fig. 1


Effects of a food-based intervention on markers of micronutrient status among Indian women of low socio-economic status.

Kehoe SH, Chopra H, Sahariah SA, Bhat D, Munshi RP, Panchal F, Young S, Brown N, Tarwande D, Gandhi M, Margetts BM, Potdar RD, Fall CH - Br. J. Nutr. (2015)

Flow chart of the study participants.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4379919&req=5

fig1: Flow chart of the study participants.
Mentions: Of the 222 women randomised, a total of 208 women with baseline blood measurements started receiving the intervention (Fig. 1). Of these, blood was collected at 12 weeks from 172 women and blood samples were available at both time points for 170 women. Compliance (defined as the proportion of women who consumed ≥ 3 snacks per week) was 85 % in the treatment and 90 % in the control groups. The median weekly snack consumption of those in the final analysis was 5·0 (IQR 4·4–5·5) in the control group and 4·9 (IQR 3·8–5·3) in the treatment group.Fig. 1

Bottom Line: We assessed the effects of group allocation on 12-week nutrient concentrations using ANCOVA models with respective 0-week concentrations, BMI, compliance, standard of living, fruit and green leafy vegetable consumption and use of synthetic nutrients as covariates.The treatment snack significantly increased β-carotene concentrations (treatment effect: 47·1 nmol/l, 95 % CI 6·5, 87·7).There was no effect of group allocation on concentrations of ferritin, retinol, ascorbate, folate or vitamin B12.

View Article: PubMed Central - PubMed

Affiliation: Medical Research Council Lifecourse Epidemiology Unit, University of Southampton,Southampton,UK.

ABSTRACT
Intakes of micronutrient-rich foods are low among Indian women of reproductive age. We investigated whether consumption of a food-based micronutrient-rich snack increased markers of blood micronutrient concentrations when compared with a control snack. Non-pregnant women (n 222) aged 14-35 years living in a Mumbai slum were randomised to receive a treatment snack (containing green leafy vegetables, dried fruit and whole milk powder), or a control snack containing foods of low micronutrient content such as wheat flour, potato and tapioca. The snacks were consumed under observation 6 d per week for 12 weeks, compliance was recorded, and blood was collected at 0 and 12 weeks. Food-frequency data were collected at both time points. Compliance (defined as the proportion of women who consumed ≥ 3 snacks/week) was >85 % in both groups. We assessed the effects of group allocation on 12-week nutrient concentrations using ANCOVA models with respective 0-week concentrations, BMI, compliance, standard of living, fruit and green leafy vegetable consumption and use of synthetic nutrients as covariates. The treatment snack significantly increased β-carotene concentrations (treatment effect: 47·1 nmol/l, 95 % CI 6·5, 87·7). There was no effect of group allocation on concentrations of ferritin, retinol, ascorbate, folate or vitamin B12. The present study shows that locally sourced foods can be made into acceptable snacks that may increase serum β-carotene concentrations among women of reproductive age. However, no increase in circulating concentrations of the other nutrients measured was observed.

Show MeSH