Limits...
Mediastinal ectopic benign colloid goitre detected using iodine-131 whole body scintigraphy and single-photon emission computed tomography-computed tomography.

Kamaleshwaran KK, Rajan F, Asokumar P, Mohanan V, Shinto AS - Indian J Nucl Med (2015 Apr-Jun)

Bottom Line: Ectopic thyroid tissue primarily occurs along the course of the embryologic migration of the thyroid gland.Primary mediastinal goiters are quite rare, occurring in <1% of all goiters.She underwent mediastinal mass excision through sternotomy and biopsy confirmed as ectopic nodular colloid goiter with no malignancy.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine, PET/CT and Radionuclide Therapy, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.

ABSTRACT
Ectopic thyroid tissue primarily occurs along the course of the embryologic migration of the thyroid gland. Mediastinal thyroid may be differentiated into primary and secondary form. Primary mediastinal goiters are quite rare, occurring in <1% of all goiters. We present findings of 29-year-old female, case of papillary carcinoma of the thyroid who underwent iodine-131 whole body scintigraphy after total thyroidectomy showed a primary mediastinal mass lesion along with residual thyroid. She underwent mediastinal mass excision through sternotomy and biopsy confirmed as ectopic nodular colloid goiter with no malignancy.

No MeSH data available.


Related in: MedlinePlus

Iodine-131 scintigraphy after 6 months showed complete ablation of the remnant thyroid
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4379686&req=5

Figure 4: Iodine-131 scintigraphy after 6 months showed complete ablation of the remnant thyroid

Mentions: A 29-year-old female presented with palpable thyroid nodule which was confirmed as papillary carcinoma, and she underwent total thyroidectomy. She was referred for I-131 WBS, which showed residual thyroid in the anterior neck along with an intense uptake in the mediastinum [Figure 1]. SPECT/CT of the chest [Figure 2] revealed an anterior mediastinal mass measuring 7 × 6 × 4 cm with calcification. Total excision of the mass with thymectomy was done, and histopathology revealed primary ectopic nodular colloid goiter with adenomatous hyperplasia with no malignancy. Thymus was separate from the lesion and had no pathological change. She underwent radioiodine ablation therapy with the dose of 100 mCi (3.7 Gbq) and post therapy I-131 WBS showed good residual thyroid uptake with no residual in mediastinum [Figure 3]. After 6 months, her thyroglobulin was <0.2 ng/ml, and I-131 WBS showed complete ablation of the residual thyroid [Figure 4].


Mediastinal ectopic benign colloid goitre detected using iodine-131 whole body scintigraphy and single-photon emission computed tomography-computed tomography.

Kamaleshwaran KK, Rajan F, Asokumar P, Mohanan V, Shinto AS - Indian J Nucl Med (2015 Apr-Jun)

Iodine-131 scintigraphy after 6 months showed complete ablation of the remnant thyroid
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4379686&req=5

Figure 4: Iodine-131 scintigraphy after 6 months showed complete ablation of the remnant thyroid
Mentions: A 29-year-old female presented with palpable thyroid nodule which was confirmed as papillary carcinoma, and she underwent total thyroidectomy. She was referred for I-131 WBS, which showed residual thyroid in the anterior neck along with an intense uptake in the mediastinum [Figure 1]. SPECT/CT of the chest [Figure 2] revealed an anterior mediastinal mass measuring 7 × 6 × 4 cm with calcification. Total excision of the mass with thymectomy was done, and histopathology revealed primary ectopic nodular colloid goiter with adenomatous hyperplasia with no malignancy. Thymus was separate from the lesion and had no pathological change. She underwent radioiodine ablation therapy with the dose of 100 mCi (3.7 Gbq) and post therapy I-131 WBS showed good residual thyroid uptake with no residual in mediastinum [Figure 3]. After 6 months, her thyroglobulin was <0.2 ng/ml, and I-131 WBS showed complete ablation of the residual thyroid [Figure 4].

Bottom Line: Ectopic thyroid tissue primarily occurs along the course of the embryologic migration of the thyroid gland.Primary mediastinal goiters are quite rare, occurring in <1% of all goiters.She underwent mediastinal mass excision through sternotomy and biopsy confirmed as ectopic nodular colloid goiter with no malignancy.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine, PET/CT and Radionuclide Therapy, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, India.

ABSTRACT
Ectopic thyroid tissue primarily occurs along the course of the embryologic migration of the thyroid gland. Mediastinal thyroid may be differentiated into primary and secondary form. Primary mediastinal goiters are quite rare, occurring in <1% of all goiters. We present findings of 29-year-old female, case of papillary carcinoma of the thyroid who underwent iodine-131 whole body scintigraphy after total thyroidectomy showed a primary mediastinal mass lesion along with residual thyroid. She underwent mediastinal mass excision through sternotomy and biopsy confirmed as ectopic nodular colloid goiter with no malignancy.

No MeSH data available.


Related in: MedlinePlus