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Duration analysis for coronary artery disease patients with chronic chest pain: an output from saudi arabia.

Hussain M, Khan N, Uddin M, Al-Nozha MM - J Cardiovasc Thorac Res (2015)

Bottom Line: Literature has found acute chest pain as plausible risk factors for CAD.The average duration was 5 years.Advancing age, female gender, no exercise and reduced high density lipoprotein (HDL) were significantly hazardous predictors throughout duration from chest pain to diagnosis of CAD.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Statistics, University of Karachi, Karachi, Pakistan ; Department of Research, Dow University of Health Sciences, Karachi, Pakistan.

ABSTRACT

Introduction: Coronary artery disease (CAD) is a persistent public health problem worldwide. Chest pain is one of the perceptible symptoms of the same disease. Literature has found acute chest pain as plausible risk factors for CAD. Nevertheless, none of the study has estimated duration from chronic chest pain to the diagnosis of CAD. The objective of the study was to estimate duration from chronic chest pain to CAD and to assess impact of risk factors on same duration.

Methods: Data were obtained from community based study on 17,232 Saudi adults. History of patients about onset of chest pain and other risk factors were inquired. Descriptive measures were obtained by Kaplan-Meier curve. Effect of demographic and clinical factors was assessed by Cox regression models.

Results: Out of 24% patients with chest pain, 21% diagnosed with CAD. The average duration was 5 years. About 12% of patients with chest pain diagnosed with CAD after one year. Advancing age, female gender, no exercise and reduced high density lipoprotein (HDL) were significantly hazardous predictors throughout duration from chest pain to diagnosis of CAD.

Conclusion: The duration from chest pain to CAD was 5 years. Age, gender, exercise and HDL can be variables of concern to deteriorate hazards of CAD for patients with chest pain.

No MeSH data available.


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Mentions: About 24% of the patients with chest pain endured CAD (Figure 2). The proportion of CAD was observed significantly more in female (P=0.004), those who did not exercise (P<0.0001), hypertensive (P<0.0001), patients having low HDL (P<0.0001), less triglyceride nitrate (P<0.0001) and low fasting triglyceride (P<0.0001).


Duration analysis for coronary artery disease patients with chronic chest pain: an output from saudi arabia.

Hussain M, Khan N, Uddin M, Al-Nozha MM - J Cardiovasc Thorac Res (2015)

© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4378676&req=5

Mentions: About 24% of the patients with chest pain endured CAD (Figure 2). The proportion of CAD was observed significantly more in female (P=0.004), those who did not exercise (P<0.0001), hypertensive (P<0.0001), patients having low HDL (P<0.0001), less triglyceride nitrate (P<0.0001) and low fasting triglyceride (P<0.0001).

Bottom Line: Literature has found acute chest pain as plausible risk factors for CAD.The average duration was 5 years.Advancing age, female gender, no exercise and reduced high density lipoprotein (HDL) were significantly hazardous predictors throughout duration from chest pain to diagnosis of CAD.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Statistics, University of Karachi, Karachi, Pakistan ; Department of Research, Dow University of Health Sciences, Karachi, Pakistan.

ABSTRACT

Introduction: Coronary artery disease (CAD) is a persistent public health problem worldwide. Chest pain is one of the perceptible symptoms of the same disease. Literature has found acute chest pain as plausible risk factors for CAD. Nevertheless, none of the study has estimated duration from chronic chest pain to the diagnosis of CAD. The objective of the study was to estimate duration from chronic chest pain to CAD and to assess impact of risk factors on same duration.

Methods: Data were obtained from community based study on 17,232 Saudi adults. History of patients about onset of chest pain and other risk factors were inquired. Descriptive measures were obtained by Kaplan-Meier curve. Effect of demographic and clinical factors was assessed by Cox regression models.

Results: Out of 24% patients with chest pain, 21% diagnosed with CAD. The average duration was 5 years. About 12% of patients with chest pain diagnosed with CAD after one year. Advancing age, female gender, no exercise and reduced high density lipoprotein (HDL) were significantly hazardous predictors throughout duration from chest pain to diagnosis of CAD.

Conclusion: The duration from chest pain to CAD was 5 years. Age, gender, exercise and HDL can be variables of concern to deteriorate hazards of CAD for patients with chest pain.

No MeSH data available.


Related in: MedlinePlus