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Falls among hemodialysis patients: potential opportunities for prevention?

Kutner NG, Zhang R, Huang Y, Wasse H - Clin Kidney J (2014)

Bottom Line: Falls were sustained by 28.4% of participants.In multivariable-adjusted analyses, participants classified as frail were over two times more likely to report falls [odds ratio (OR): 2.39, 95% confidence interval (CI): 1.22-4.71, P = 0.01], and participants with a CES-D score 18+ and/or prescribed antidepressants were over 80% more likely to be fallers (OR: 1.83, 95% CI: 1.23-2.74, P = 0.003) than were participants with a CES-D score <18 and no prescribed antidepressants.Frailty and depressed mood, factors that are potentially modifiable, are prominently associated with falls.

View Article: PubMed Central - PubMed

Affiliation: United States Renal Data System , Rehabilitation/Quality of Life Special Studies Center , Emory University , Atlanta, GA , USA.

ABSTRACT

Background: Falls among patients undergoing maintenance hemodialysis (HD) have significant consequences for quality of life and functional independence, morbidity, healthcare utilization and even mortality, but studies on the etiology of falls within large HD cohorts are limited.

Methods: Falls during the past 12 months were ascertained for a prevalent multi-center HD cohort (n = 762) aged 20-92 years, and associations with demographic and treatment characteristics, comorbidities, cognitive function, prescribed medications, balance tests, frailty and depressive symptoms were assessed.

Results: Falls were sustained by 28.4% of participants. In multivariable-adjusted analyses, participants classified as frail were over two times more likely to report falls [odds ratio (OR): 2.39, 95% confidence interval (CI): 1.22-4.71, P = 0.01], and participants with a CES-D score 18+ and/or prescribed antidepressants were over 80% more likely to be fallers (OR: 1.83, 95% CI: 1.23-2.74, P = 0.003) than were participants with a CES-D score <18 and no prescribed antidepressants.

Conclusions: Frailty and depressed mood, factors that are potentially modifiable, are prominently associated with falls.

No MeSH data available.


Related in: MedlinePlus

Fall rates by age category of study participants.
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SFU034F3: Fall rates by age category of study participants.

Mentions: This study, consistent with previous research (Table 1), found that falls are likely to occur annually among 25% or more of HD patients, even in a cohort that is not primarily elderly. Figure 3 shows the rate of falls by age group of study participants. Falls were more common among patients aged 45–64 years than those aged 65–74 years and were almost as common as in patients aged 75+.Fig. 3.


Falls among hemodialysis patients: potential opportunities for prevention?

Kutner NG, Zhang R, Huang Y, Wasse H - Clin Kidney J (2014)

Fall rates by age category of study participants.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4377754&req=5

SFU034F3: Fall rates by age category of study participants.
Mentions: This study, consistent with previous research (Table 1), found that falls are likely to occur annually among 25% or more of HD patients, even in a cohort that is not primarily elderly. Figure 3 shows the rate of falls by age group of study participants. Falls were more common among patients aged 45–64 years than those aged 65–74 years and were almost as common as in patients aged 75+.Fig. 3.

Bottom Line: Falls were sustained by 28.4% of participants.In multivariable-adjusted analyses, participants classified as frail were over two times more likely to report falls [odds ratio (OR): 2.39, 95% confidence interval (CI): 1.22-4.71, P = 0.01], and participants with a CES-D score 18+ and/or prescribed antidepressants were over 80% more likely to be fallers (OR: 1.83, 95% CI: 1.23-2.74, P = 0.003) than were participants with a CES-D score <18 and no prescribed antidepressants.Frailty and depressed mood, factors that are potentially modifiable, are prominently associated with falls.

View Article: PubMed Central - PubMed

Affiliation: United States Renal Data System , Rehabilitation/Quality of Life Special Studies Center , Emory University , Atlanta, GA , USA.

ABSTRACT

Background: Falls among patients undergoing maintenance hemodialysis (HD) have significant consequences for quality of life and functional independence, morbidity, healthcare utilization and even mortality, but studies on the etiology of falls within large HD cohorts are limited.

Methods: Falls during the past 12 months were ascertained for a prevalent multi-center HD cohort (n = 762) aged 20-92 years, and associations with demographic and treatment characteristics, comorbidities, cognitive function, prescribed medications, balance tests, frailty and depressive symptoms were assessed.

Results: Falls were sustained by 28.4% of participants. In multivariable-adjusted analyses, participants classified as frail were over two times more likely to report falls [odds ratio (OR): 2.39, 95% confidence interval (CI): 1.22-4.71, P = 0.01], and participants with a CES-D score 18+ and/or prescribed antidepressants were over 80% more likely to be fallers (OR: 1.83, 95% CI: 1.23-2.74, P = 0.003) than were participants with a CES-D score <18 and no prescribed antidepressants.

Conclusions: Frailty and depressed mood, factors that are potentially modifiable, are prominently associated with falls.

No MeSH data available.


Related in: MedlinePlus