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Magnetic resonance imaging of sellar and juxtasellar abnormalities in the paediatric population: an imaging review.

Shields R, Mangla R, Almast J, Meyers S - Insights Imaging (2015)

Bottom Line: The sellar and juxtasellar regions in the paediatric population are complex both anatomically and pathologically, with magnetic resonance imaging (MRI) being the "gold standard" imaging modality due to the high contrast of detail.Assessment requires a detailed understanding of the anatomy, embryology, pathophysiology and normal signal characteristics of the pituitary gland and surrounding structures in order to appropriately characterise abnormalities.This article aims to provide an overview of the imaging characteristics of developmental/congenital and acquired disease processes which affect the sellar and juxtasellar region in the paediatric population.

View Article: PubMed Central - PubMed

Affiliation: Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, NY, 14642-0001, USA, rachel_shields@urmc.rochester.edu.

ABSTRACT
The sellar and juxtasellar regions in the paediatric population are complex both anatomically and pathologically, with magnetic resonance imaging (MRI) being the "gold standard" imaging modality due to the high contrast of detail. Assessment requires a detailed understanding of the anatomy, embryology, pathophysiology and normal signal characteristics of the pituitary gland and surrounding structures in order to appropriately characterise abnormalities. This article aims to provide an overview of the imaging characteristics of developmental/congenital and acquired disease processes which affect the sellar and juxtasellar region in the paediatric population. Main Messages • The sellar region is anatomically complex and covers a wide pathology spectrum. • MRI is the key imaging modality to assess sellar and juxtasellar pathology. • Numerous developmental anomalies may not be discovered until adulthood. • Knowledge of pathology alerts and guides the clinician towards appropriate management.

No MeSH data available.


Related in: MedlinePlus

Empty sella. Sagittal post-contrast T1WI with fat-suppression show an enlarged sella mostly filled with CSF. The enhancing flattened pituitary tissue is located along the floor of the sella
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Fig18: Empty sella. Sagittal post-contrast T1WI with fat-suppression show an enlarged sella mostly filled with CSF. The enhancing flattened pituitary tissue is located along the floor of the sella

Mentions: Benign fatty lesions resulting from a congenital malformation, often located at or near the midline. In the sellar region, they occur along the surface of the infundibulum, floor of the third ventricle, or adjacent to cranial nerves, and are usually discovered incidentally, unless they cause a mass effect [42, 43]. They may contain calcifications and/or traverse blood vessels. MRI signal is isointense to subcutaneous fat on all sequences, with fat suppressed images useful in distinguishing from haemorrhagic or proteinaceous lesions.


Magnetic resonance imaging of sellar and juxtasellar abnormalities in the paediatric population: an imaging review.

Shields R, Mangla R, Almast J, Meyers S - Insights Imaging (2015)

Empty sella. Sagittal post-contrast T1WI with fat-suppression show an enlarged sella mostly filled with CSF. The enhancing flattened pituitary tissue is located along the floor of the sella
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4376809&req=5

Fig18: Empty sella. Sagittal post-contrast T1WI with fat-suppression show an enlarged sella mostly filled with CSF. The enhancing flattened pituitary tissue is located along the floor of the sella
Mentions: Benign fatty lesions resulting from a congenital malformation, often located at or near the midline. In the sellar region, they occur along the surface of the infundibulum, floor of the third ventricle, or adjacent to cranial nerves, and are usually discovered incidentally, unless they cause a mass effect [42, 43]. They may contain calcifications and/or traverse blood vessels. MRI signal is isointense to subcutaneous fat on all sequences, with fat suppressed images useful in distinguishing from haemorrhagic or proteinaceous lesions.

Bottom Line: The sellar and juxtasellar regions in the paediatric population are complex both anatomically and pathologically, with magnetic resonance imaging (MRI) being the "gold standard" imaging modality due to the high contrast of detail.Assessment requires a detailed understanding of the anatomy, embryology, pathophysiology and normal signal characteristics of the pituitary gland and surrounding structures in order to appropriately characterise abnormalities.This article aims to provide an overview of the imaging characteristics of developmental/congenital and acquired disease processes which affect the sellar and juxtasellar region in the paediatric population.

View Article: PubMed Central - PubMed

Affiliation: Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, NY, 14642-0001, USA, rachel_shields@urmc.rochester.edu.

ABSTRACT
The sellar and juxtasellar regions in the paediatric population are complex both anatomically and pathologically, with magnetic resonance imaging (MRI) being the "gold standard" imaging modality due to the high contrast of detail. Assessment requires a detailed understanding of the anatomy, embryology, pathophysiology and normal signal characteristics of the pituitary gland and surrounding structures in order to appropriately characterise abnormalities. This article aims to provide an overview of the imaging characteristics of developmental/congenital and acquired disease processes which affect the sellar and juxtasellar region in the paediatric population. Main Messages • The sellar region is anatomically complex and covers a wide pathology spectrum. • MRI is the key imaging modality to assess sellar and juxtasellar pathology. • Numerous developmental anomalies may not be discovered until adulthood. • Knowledge of pathology alerts and guides the clinician towards appropriate management.

No MeSH data available.


Related in: MedlinePlus