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Porokeratotic eccrine ostial and dermal duct nevus.

Bandyopadhyay D, Saha A, Das D, Das A - Indian Dermatol Online J (2015 Mar-Apr)

Bottom Line: Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nevoid condition characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities, having distinct porokeratotic histopathological features.The lesions usually present at birth or in childhood.We present here a case of late-onset PEODDN in a 23-year-old man who had lesions on the palm, forearm, arm and the chest along the lines of Blaschko, strictly localized to the left side of the body.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Medical College, Kolkata, West Bengal, India.

ABSTRACT
Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nevoid condition characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities, having distinct porokeratotic histopathological features. The lesions usually present at birth or in childhood. We present here a case of late-onset PEODDN in a 23-year-old man who had lesions on the palm, forearm, arm and the chest along the lines of Blaschko, strictly localized to the left side of the body.

No MeSH data available.


Related in: MedlinePlus

Multiple cornoid lamella-like keratotic invaginations of the epidermis (H and E, ×50)
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Figure 5: Multiple cornoid lamella-like keratotic invaginations of the epidermis (H and E, ×50)

Mentions: We considered linear lichen planus, nevus comedonicus and PEODDN as differentials and skin biopsy specimens were obtained. Histopathology showed hyperkeratosis, acanthosis and papillomatosis and no dermal infiltrate. Cornoid lamella-like columns of parakeratosis were seen invaginating the epidermis. Granular layer were absent beneath these columns [Figures 4 and 5]. Dilated acrosyringia were however not visualized in the sections examined. The absence of interface dermatitis ruled out lichen planus. Nevus comedonicus was excluded by the absence of grouped undeveloped hair follicles filled with cornified debris devoid of hair shafts. Linear porokeratosis was not included in the differentials as the patient did not have the characteristic plaques with furrowed borders. Based on the distinct clinical findings corroborated by the histology, the case was diagnosed as PEODDN and the patient was referred for ablative laser therapy.


Porokeratotic eccrine ostial and dermal duct nevus.

Bandyopadhyay D, Saha A, Das D, Das A - Indian Dermatol Online J (2015 Mar-Apr)

Multiple cornoid lamella-like keratotic invaginations of the epidermis (H and E, ×50)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4375756&req=5

Figure 5: Multiple cornoid lamella-like keratotic invaginations of the epidermis (H and E, ×50)
Mentions: We considered linear lichen planus, nevus comedonicus and PEODDN as differentials and skin biopsy specimens were obtained. Histopathology showed hyperkeratosis, acanthosis and papillomatosis and no dermal infiltrate. Cornoid lamella-like columns of parakeratosis were seen invaginating the epidermis. Granular layer were absent beneath these columns [Figures 4 and 5]. Dilated acrosyringia were however not visualized in the sections examined. The absence of interface dermatitis ruled out lichen planus. Nevus comedonicus was excluded by the absence of grouped undeveloped hair follicles filled with cornified debris devoid of hair shafts. Linear porokeratosis was not included in the differentials as the patient did not have the characteristic plaques with furrowed borders. Based on the distinct clinical findings corroborated by the histology, the case was diagnosed as PEODDN and the patient was referred for ablative laser therapy.

Bottom Line: Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nevoid condition characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities, having distinct porokeratotic histopathological features.The lesions usually present at birth or in childhood.We present here a case of late-onset PEODDN in a 23-year-old man who had lesions on the palm, forearm, arm and the chest along the lines of Blaschko, strictly localized to the left side of the body.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Medical College, Kolkata, West Bengal, India.

ABSTRACT
Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nevoid condition characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities, having distinct porokeratotic histopathological features. The lesions usually present at birth or in childhood. We present here a case of late-onset PEODDN in a 23-year-old man who had lesions on the palm, forearm, arm and the chest along the lines of Blaschko, strictly localized to the left side of the body.

No MeSH data available.


Related in: MedlinePlus