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Spatio-temporal analysis of the relationship between climate and hand, foot, and mouth disease in Shandong province, China, 2008-2012.

Liu Y, Wang X, Pang C, Yuan Z, Li H, Xue F - BMC Infect. Dis. (2015)

Bottom Line: The best fitting Spatio-temporal interactive model showed that annual average temperature, annual average pressure, annual average relative humidity, annual average wind speed and annual sunshine hours were significantly positive related to the occurrence of HFMD.The estimated relative risk of 36, 87, 91, 79, 65 out of 140 counties for 2008-2012 respectively were significantly more than 1.There were obvious spatio-temporal heterogeneity of HFMD in Shandong Province, and the climatic indicators were associated with the epidemic of HFMD.

View Article: PubMed Central - PubMed

Affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, China. yunxialiu@163.com.

ABSTRACT

Background: Hand, foot, and mouth disease (HFMD) is the most common communicable disease in China. Shandong Province is one of the most seriously affected areas. The distribution of HFMD had spatial heterogeneity and seasonal characteristic in this setting. The aim of this study was to explore the associations between climate and HFMD by a Bayesian approach from spatio-temporal interactions perspective.

Methods: The HFMD data of Shandong Province during 2008-2012 were derived from the China National Disease Surveillance Reporting and Management System. And six climatic indicators were obtained from the Meteorological Bureau of Shandong Province. The global spatial autocorrelation statistic (Moran's I) was used to detect the spatial autocorrelation of HFMD cases in each year. The optimal one among four Bayesian models was further adopted to estimate the relative risk of the occurrence of HFMD via Markov chain Monte Carlo.

Results: The annual average incidence rate of HFMD was 104.40 per 100,000 in Shandong Province. Positive spatial autocorrelation appeared at county level (Moran's I≥0.30, P<0.001). The best fitting Spatio-temporal interactive model showed that annual average temperature, annual average pressure, annual average relative humidity, annual average wind speed and annual sunshine hours were significantly positive related to the occurrence of HFMD. The estimated relative risk of 36, 87, 91, 79, 65 out of 140 counties for 2008-2012 respectively were significantly more than 1.

Conclusions: There were obvious spatio-temporal heterogeneity of HFMD in Shandong Province, and the climatic indicators were associated with the epidemic of HFMD. Bayesian approach should be recommended to capture the spatial-temporal pattern of HFMD.

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Related in: MedlinePlus

The location of study area, Shandong Province in China.
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Fig1: The location of study area, Shandong Province in China.

Mentions: We performed this ecological spatial study of HFMD in Shandong Province (Figure 1), a coastal province in Eastern China with a population of approximately 97.33 million in 2013 [36]. Its area of 156,700 square kilometers was divided into 17 municipal districts which including 140 subdistricts (counties). Considering the county administrative level was often used for the HFMD-decision making process in China [27], county was used as the spatial unit of analysis (Figure 1).Figure 1


Spatio-temporal analysis of the relationship between climate and hand, foot, and mouth disease in Shandong province, China, 2008-2012.

Liu Y, Wang X, Pang C, Yuan Z, Li H, Xue F - BMC Infect. Dis. (2015)

The location of study area, Shandong Province in China.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4374415&req=5

Fig1: The location of study area, Shandong Province in China.
Mentions: We performed this ecological spatial study of HFMD in Shandong Province (Figure 1), a coastal province in Eastern China with a population of approximately 97.33 million in 2013 [36]. Its area of 156,700 square kilometers was divided into 17 municipal districts which including 140 subdistricts (counties). Considering the county administrative level was often used for the HFMD-decision making process in China [27], county was used as the spatial unit of analysis (Figure 1).Figure 1

Bottom Line: The best fitting Spatio-temporal interactive model showed that annual average temperature, annual average pressure, annual average relative humidity, annual average wind speed and annual sunshine hours were significantly positive related to the occurrence of HFMD.The estimated relative risk of 36, 87, 91, 79, 65 out of 140 counties for 2008-2012 respectively were significantly more than 1.There were obvious spatio-temporal heterogeneity of HFMD in Shandong Province, and the climatic indicators were associated with the epidemic of HFMD.

View Article: PubMed Central - PubMed

Affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, China. yunxialiu@163.com.

ABSTRACT

Background: Hand, foot, and mouth disease (HFMD) is the most common communicable disease in China. Shandong Province is one of the most seriously affected areas. The distribution of HFMD had spatial heterogeneity and seasonal characteristic in this setting. The aim of this study was to explore the associations between climate and HFMD by a Bayesian approach from spatio-temporal interactions perspective.

Methods: The HFMD data of Shandong Province during 2008-2012 were derived from the China National Disease Surveillance Reporting and Management System. And six climatic indicators were obtained from the Meteorological Bureau of Shandong Province. The global spatial autocorrelation statistic (Moran's I) was used to detect the spatial autocorrelation of HFMD cases in each year. The optimal one among four Bayesian models was further adopted to estimate the relative risk of the occurrence of HFMD via Markov chain Monte Carlo.

Results: The annual average incidence rate of HFMD was 104.40 per 100,000 in Shandong Province. Positive spatial autocorrelation appeared at county level (Moran's I≥0.30, P<0.001). The best fitting Spatio-temporal interactive model showed that annual average temperature, annual average pressure, annual average relative humidity, annual average wind speed and annual sunshine hours were significantly positive related to the occurrence of HFMD. The estimated relative risk of 36, 87, 91, 79, 65 out of 140 counties for 2008-2012 respectively were significantly more than 1.

Conclusions: There were obvious spatio-temporal heterogeneity of HFMD in Shandong Province, and the climatic indicators were associated with the epidemic of HFMD. Bayesian approach should be recommended to capture the spatial-temporal pattern of HFMD.

Show MeSH
Related in: MedlinePlus