Limits...
Appraisal of the remineralizing potential of child formula dentifrices on primary teeth: An in vitro pH cycling model.

Kiranmayi M, Nirmala SV, Nuvvula S - Contemp Clin Dent (2015)

Bottom Line: Twenty-one primary teeth were placed in demineralizing solution for 96 h to produce artificial carious lesions; then cut longitudinally into 100-150 μm thick sections and randomly assigned to three groups.Though dentifrices containing 458 ppm MFP and 500 ppm NaF demonstrated remineralization of carious lesions, it was not complete.Therefore, it is also important to emphasize on other preventive methods in the prevention and/or reversal of carious lesions.

View Article: PubMed Central - PubMed

Affiliation: Department of Paedodontics and Preventive Dentistry, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.

ABSTRACT

Aim: To evaluate the remineralizing potential of child formula dentifrices on primary teeth using an in vitro 7 days pH cycling model.

Materials and methods: Twenty-one primary teeth were placed in demineralizing solution for 96 h to produce artificial carious lesions; then cut longitudinally into 100-150 μm thick sections and randomly assigned to three groups. Sections in Group A were treated with dentifrice containing 458 ppm monofluorophosphate (MFP) and sections in Group B with 500 ppm sodium fluoride (NaF). Group C sections were treated with a nonfluoridated dentifrice.

Results: Group A (458 ppm MFP) and Group B (500 ppm NaF) showed significant decrease in lesion depth, whereas Group C (non F) showed a significant increase in depth (P ≤ 0.05, paired t-test).

Conclusion: Though dentifrices containing 458 ppm MFP and 500 ppm NaF demonstrated remineralization of carious lesions, it was not complete. Therefore, it is also important to emphasize on other preventive methods in the prevention and/or reversal of carious lesions.

No MeSH data available.


Related in: MedlinePlus

Polarized light micrographs of enamel lesions before (a) and after (b) pH cycling for Group A
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4374326&req=5

Figure 1: Polarized light micrographs of enamel lesions before (a) and after (b) pH cycling for Group A

Mentions: For clear demarcation between sound and carious enamel, the specimens were imbibed in water and then recorded using polarizing light microscope both before and after pH-cycling, to evaluate qualitatively the lesion depth in each enamel section [Figures 1–3]. The depths of the lesions were measured with a computerized calculation method using a software program (ProgRes®, Germany).


Appraisal of the remineralizing potential of child formula dentifrices on primary teeth: An in vitro pH cycling model.

Kiranmayi M, Nirmala SV, Nuvvula S - Contemp Clin Dent (2015)

Polarized light micrographs of enamel lesions before (a) and after (b) pH cycling for Group A
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4374326&req=5

Figure 1: Polarized light micrographs of enamel lesions before (a) and after (b) pH cycling for Group A
Mentions: For clear demarcation between sound and carious enamel, the specimens were imbibed in water and then recorded using polarizing light microscope both before and after pH-cycling, to evaluate qualitatively the lesion depth in each enamel section [Figures 1–3]. The depths of the lesions were measured with a computerized calculation method using a software program (ProgRes®, Germany).

Bottom Line: Twenty-one primary teeth were placed in demineralizing solution for 96 h to produce artificial carious lesions; then cut longitudinally into 100-150 μm thick sections and randomly assigned to three groups.Though dentifrices containing 458 ppm MFP and 500 ppm NaF demonstrated remineralization of carious lesions, it was not complete.Therefore, it is also important to emphasize on other preventive methods in the prevention and/or reversal of carious lesions.

View Article: PubMed Central - PubMed

Affiliation: Department of Paedodontics and Preventive Dentistry, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.

ABSTRACT

Aim: To evaluate the remineralizing potential of child formula dentifrices on primary teeth using an in vitro 7 days pH cycling model.

Materials and methods: Twenty-one primary teeth were placed in demineralizing solution for 96 h to produce artificial carious lesions; then cut longitudinally into 100-150 μm thick sections and randomly assigned to three groups. Sections in Group A were treated with dentifrice containing 458 ppm monofluorophosphate (MFP) and sections in Group B with 500 ppm sodium fluoride (NaF). Group C sections were treated with a nonfluoridated dentifrice.

Results: Group A (458 ppm MFP) and Group B (500 ppm NaF) showed significant decrease in lesion depth, whereas Group C (non F) showed a significant increase in depth (P ≤ 0.05, paired t-test).

Conclusion: Though dentifrices containing 458 ppm MFP and 500 ppm NaF demonstrated remineralization of carious lesions, it was not complete. Therefore, it is also important to emphasize on other preventive methods in the prevention and/or reversal of carious lesions.

No MeSH data available.


Related in: MedlinePlus