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Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation.

Misra SR, Shankar YU, Rastogi V, Maragathavalli G - Contemp Clin Dent (2015)

Bottom Line: Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement.Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge.A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubaneswar, Odisha, India.

ABSTRACT
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

No MeSH data available.


Related in: MedlinePlus

Ultrasonography of the abdomen revealed a large lesion in the left lobe of the liver and another lesion in the right lobe. Both lesions were irregular and hypoechoic with multiple septa within the lesion
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Figure 8: Ultrasonography of the abdomen revealed a large lesion in the left lobe of the liver and another lesion in the right lobe. Both lesions were irregular and hypoechoic with multiple septa within the lesion

Mentions: Ultrasonography of the abdomen revealed a large lesion in the left lobe of the liver and another lesion in the right lobe. The lesions were irregular with multiple septa within. Two irregular, hypoechoic lesions in the left and right lobe of the liver were observed. Abdominal ultrasound examination revealed hypoechoic mass in the liver [Figure 8].


Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation.

Misra SR, Shankar YU, Rastogi V, Maragathavalli G - Contemp Clin Dent (2015)

Ultrasonography of the abdomen revealed a large lesion in the left lobe of the liver and another lesion in the right lobe. Both lesions were irregular and hypoechoic with multiple septa within the lesion
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4374307&req=5

Figure 8: Ultrasonography of the abdomen revealed a large lesion in the left lobe of the liver and another lesion in the right lobe. Both lesions were irregular and hypoechoic with multiple septa within the lesion
Mentions: Ultrasonography of the abdomen revealed a large lesion in the left lobe of the liver and another lesion in the right lobe. The lesions were irregular with multiple septa within. Two irregular, hypoechoic lesions in the left and right lobe of the liver were observed. Abdominal ultrasound examination revealed hypoechoic mass in the liver [Figure 8].

Bottom Line: Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement.Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge.A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubaneswar, Odisha, India.

ABSTRACT
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

No MeSH data available.


Related in: MedlinePlus