Limits...
Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation.

Misra SR, Shankar YU, Rastogi V, Maragathavalli G - Contemp Clin Dent (2015)

Bottom Line: Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement.Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge.A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubaneswar, Odisha, India.

ABSTRACT
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

No MeSH data available.


Related in: MedlinePlus

(a) Contrast-enhanced coronal computed tomography scan showed a lytic destructive lesion involving left anterior mandibular region with external soft tissue component. (b) An irregular cortical defect in the anterior margin of right mandibular angle/ascending ramus was observed with a large solid enhancing mass having few internal calcifications and regional pressure effect on the right masseteric and buccal spaces with scalloping and erosion of posterior wall of the right maxillary antrum seen in axial section
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4374307&req=5

Figure 5: (a) Contrast-enhanced coronal computed tomography scan showed a lytic destructive lesion involving left anterior mandibular region with external soft tissue component. (b) An irregular cortical defect in the anterior margin of right mandibular angle/ascending ramus was observed with a large solid enhancing mass having few internal calcifications and regional pressure effect on the right masseteric and buccal spaces with scalloping and erosion of posterior wall of the right maxillary antrum seen in axial section

Mentions: Computed tomography scan showed a lytic destructive lesion involving left anterior mandibular region with external soft tissue component. An irregular cortical defect in the anterior margin of right mandibular angle/ascending ramus was observed [Figure 4]with a large solid enhancing mass having few internal calcifications and regional pressure effect on the right masseteric and buccal spaces with scalloping and erosion of posterior wall of the right maxillary antrum [Figure 5a and b].


Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation.

Misra SR, Shankar YU, Rastogi V, Maragathavalli G - Contemp Clin Dent (2015)

(a) Contrast-enhanced coronal computed tomography scan showed a lytic destructive lesion involving left anterior mandibular region with external soft tissue component. (b) An irregular cortical defect in the anterior margin of right mandibular angle/ascending ramus was observed with a large solid enhancing mass having few internal calcifications and regional pressure effect on the right masseteric and buccal spaces with scalloping and erosion of posterior wall of the right maxillary antrum seen in axial section
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4374307&req=5

Figure 5: (a) Contrast-enhanced coronal computed tomography scan showed a lytic destructive lesion involving left anterior mandibular region with external soft tissue component. (b) An irregular cortical defect in the anterior margin of right mandibular angle/ascending ramus was observed with a large solid enhancing mass having few internal calcifications and regional pressure effect on the right masseteric and buccal spaces with scalloping and erosion of posterior wall of the right maxillary antrum seen in axial section
Mentions: Computed tomography scan showed a lytic destructive lesion involving left anterior mandibular region with external soft tissue component. An irregular cortical defect in the anterior margin of right mandibular angle/ascending ramus was observed [Figure 4]with a large solid enhancing mass having few internal calcifications and regional pressure effect on the right masseteric and buccal spaces with scalloping and erosion of posterior wall of the right maxillary antrum [Figure 5a and b].

Bottom Line: Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement.Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge.A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubaneswar, Odisha, India.

ABSTRACT
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

No MeSH data available.


Related in: MedlinePlus